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Advanced filters: Author: Amina Houddane Clear advanced filters

  • The glycolytic enzymes GAPDH and pyruvate kinase produce 4-phosphoerythronate and 2-phospho-L-lactate, which block metabolic flux. A newly identified conserved metabolic repair enzyme, phosphoglycolate phosphatase, eliminates these side products.

    • François Collard
    • Francesca Baldin
    • Guido T Bommer
    Research
    Nature Chemical Biology
    Volume: 12, P: 601-607