Nature Search

The emergence of circadian timekeeping in the intestine

Circadian rhythms are present in cells throughout the body but how these develop is poorly understood. Here, using Drosophila genetics and single cell analysis, authors find that the intestinal clock emerges after development is complete, and that differentiation disrupts its function.

Kathyani Parasram
Amy Zuccato
Phillip Karpowicz
ResearchOpen Access27 Feb 2024
Nature Communications

Volume: 15, P: 1-15
Characterising acute and chronic care needs: insights from the Global Burden of Disease Study 2019

Chronic care manages long-term, progressive conditions, while acute care handles short-term ones. Here, authors show chronic conditions account for most of the global health burden, with 68% of DALYs and 93% of YLDs attributed to chronic care needs.

Cecilia Anza-Ramirez
J. Jaime Miranda
Yves Miel H. Zuniga
ResearchOpen Access07 May 2025
Nature Communications

Volume: 16, P: 1-36
DNA-binding properties of the yeast SWI/SNF complex

Janet Quinn
Amy M. Fyrberg
Craig L. Peterson
Research29 Feb 1996
Nature

Volume: 379, P: 844-847
A metagenomic DNA sequencing assay that is robust against environmental DNA contamination

The accuracy of metagenomic DNA sequencing is limited by environmental DNA contamination. Here, the authors develop and test SIFT-seq, a metagenomic DNA sequencing assay that allows to identify and remove environmental DNA contamination introduced during sample preparation.

Omary Mzava
Alexandre Pellan Cheng
Iwijn De Vlaminck
ResearchOpen Access21 Jul 2022
Nature Communications

Volume: 13, P: 1-10
Experimental colitis in SIV-uninfected rhesus macaques recapitulates important features of pathogenic SIV infection

HIV-1 infection in humans and SIV infection in rhesus macaques are associated with mucosal damage to the gastrointestinal tract, microbial translocation and chronic immune activation. Here the authors develop a non-human primate DSS colitis model that recapitulates these aspects of the disease in uninfected rhesus macaques.

Xing Pei Hao
Carissa M. Lucero
Jacob D. Estes
ResearchOpen Access18 Aug 2015
Nature Communications

Volume: 6, P: 1-12
Author Correction: Myeloid lineage enhancers drive oncogene synergy in CEBPA/CSF3R mutant acute myeloid leukemia

Theodore P. Braun
Mariam Okhovat
Julia E. Maxson
Amendments and CorrectionsOpen Access16 Jun 2022
Nature Communications

Volume: 13, P: 1
Animal cryptochromes mediate magnetoreception by an unconventional photochemical mechanism

Animals use the Earth's magnetic field for orientation but the biophysical basis of this is unclear. The light-dependent magnetic sense of Drosophila melanogaster was recently shown to be mediated by the cryptochrome (Cry) photoreceptor; here, using a transgenic approach, the type 1 and 2 Cry of the monarch butterfly are shown to both function in the magnetoreception system of Drosophila, and probably use an unconventional photochemical mechanism.

Robert J. Gegear
Lauren E. Foley
Steven M. Reppert
Research24 Jan 2010
Nature

Volume: 463, P: 804-807
Myeloid lineage enhancers drive oncogene synergy in CEBPA/CSF3R mutant acute myeloid leukemia

Acute Myeloid Leukemia (AML) develops following multiple mutations of differing impact. Here, the authors show that activating mutations of CSF3R co-operate with loss-of-function mutations of CEBPA to promote AML development through an enhancer-dependent mechanism.

Theodore P. Braun
Mariam Okhovat
Julia E. Maxson
ResearchOpen Access29 Nov 2019
Nature Communications

Volume: 10, P: 1-15
Activation and repression of p21^WAF1/CIP1 transcription by RB binding proteins

Andrei L Gartel
Eugene Goufman
Angela L Tyner
Research13 Jan 1999
Oncogene

Volume: 17, P: 3463-3469
In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes

Previous work has shown that a combination of three transcription factors can directly reprogram cardiac fibroblasts into cardiomyocyte-like cell in vitro; now, the same authors demonstrate in vivo reprogramming of cardiac fibroblasts into induced cardiomyocytes.

Li Qian
Yu Huang
Deepak Srivastava
Research18 Apr 2012
Nature

Volume: 485, P: 593-598
Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia

Pappalardi and colleagues identify a potent noncovalent DNMT1-selective inhibitor with improved tolerability and efficacy in preclinical AML models compared with clinically validated covalent pan-DNMT inhibitors.

Melissa B. Pappalardi
Kathryn Keenan
Michael T. McCabe
Research27 Sept 2021
Nature Cancer

Volume: 2, P: 1002-1017
Antibody decay, T cell immunity and breakthrough infections following two SARS-CoV-2 vaccine doses in inflammatory bowel disease patients treated with infliximab and vedolizumab

Vaccination is effective in protecting from COVID-19. Here the authors report immune responses and breakthrough infections in twice-vaccinated patients receiving anti-TNF treatments for inflammatory bowel disease, and find dampened vaccine responses that implicate the need of adapted vaccination schedules for these patients.

Simeng Lin
Nicholas A. Kennedy
Jeannie Bishop
ResearchOpen Access16 Mar 2022
Nature Communications

Volume: 13, P: 1-14
Cryptochrome mediates light-dependent magnetosensitivity in Drosophila

Robert J. Gegear
Amy Casselman
Steven M. Reppert
Research20 Jul 2008
Nature

Volume: 454, P: 1014-1018
Evolution of genes and genomes on the Drosophila phylogeny

An international consortium reports the genomic sequence for ten Drosophila species, and compares them to two other previously published Drosophila species. These data are invaluable for drawing evolutionary conclusions across an entire phylogeny of species at once.

Andrew G. Clark
Michael B. Eisen
Iain MacCallum
Research08 Nov 2007
Nature

Volume: 450, P: 203-218
Proton Radiography Peers into Metal Solidification

Amy Clarke
Seth Imhoff
David Teter
ResearchOpen Access19 Jun 2013
Scientific Reports

Volume: 3, P: 1-6
Maintenance of pig brain function under extracorporeal pulsatile circulatory control (EPCC)

Muhammed Shariff
Aksharkumar Dobariya
Juan M. Pascual
ResearchOpen Access25 Aug 2023
Scientific Reports

Volume: 13, P: 1-16
At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods

Munib Mesinovic
Xin Ci Wong
David Zucman
ResearchOpen Access16 Jul 2024
Scientific Reports

Volume: 14, P: 1-43
Mutant SETBP1 enhances NRAS-driven MAPK pathway activation to promote aggressive leukemia

Sarah A. Carratt
Theodore P. Braun
Julia E. Maxson
Research17 May 2021
Leukemia

Volume: 35, P: 3594-3599
Correction: Mutant SETBP1 enhances NRAS-driven MAPK pathway activation to promote aggressive leukemia

Sarah A. Carratt
Theodore P. Braun
Julia E. Maxson
Amendments and Corrections06 Jul 2022
Leukemia

Volume: 36, P: 2149
Morphodynamic evolution following sediment release from the world’s largest dam removal

Andrew C. Ritchie
Jonathan A. Warrick
Andrea S. Ogston
ResearchOpen Access05 Sept 2018
Scientific Reports

Volume: 8, P: 1-13
Shared mechanisms between coronary heart disease and depression: findings from a large UK general population-based cohort

Golam M. Khandaker
Verena Zuber
Stephen Burgess
ResearchOpen Access19 Mar 2019
Molecular Psychiatry

Volume: 25, P: 1477-1486
Real-time metabolic profiling of oesophageal tumours reveals an altered metabolic phenotype to different oxygen tensions and to treatment with Pyrazinib

Amy M. Buckley
Margaret R. Dunne
Jacintha O’Sullivan
ResearchOpen Access21 Jul 2020
Scientific Reports

Volume: 10, P: 1-16
Four consecutive yearly point-prevalence studies in Wales indicate lack of improvement in sepsis care on the wards

Maja Kopczynska
Harry Unwin
Judith E. Hall
ResearchOpen Access10 Aug 2021
Scientific Reports

Volume: 11, P: 1-12
Delineating COVID-19 subgroups using routine clinical data identifies distinct in-hospital outcomes

Bojidar Rangelov
Alexandra Young
Mark Radon
ResearchOpen Access20 Jun 2023
Scientific Reports

Volume: 13, P: 1-14
ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19

Ali Abbas
Sheryl Ann Abdukahil
Luis Felipe Reyes
ResearchOpen Access30 Jul 2022
Scientific Data

Volume: 9, P: 1-22
Correction: Shared mechanisms between coronary heart disease and depression: findings from a large UK general population-based cohort

Golam M. Khandaker
Verena Zuber
Stephen Burgess
Amendments and CorrectionsOpen Access17 Aug 2020
Molecular Psychiatry

Volume: 26, P: 3659-3661
Author Correction: Delineating COVID-19 subgroups using routine clinical data identifies distinct in-hospital outcomes

Bojidar Rangelov
Alexandra Young
Mark Radon
Amendments and CorrectionsOpen Access26 Oct 2023
Scientific Reports

Volume: 13, P: 1

Search

The emergence of circadian timekeeping in the intestine

Characterising acute and chronic care needs: insights from the Global Burden of Disease Study 2019

DNA-binding properties of the yeast SWI/SNF complex

A metagenomic DNA sequencing assay that is robust against environmental DNA contamination

Experimental colitis in SIV-uninfected rhesus macaques recapitulates important features of pathogenic SIV infection

Author Correction: Myeloid lineage enhancers drive oncogene synergy in CEBPA/CSF3R mutant acute myeloid leukemia

Animal cryptochromes mediate magnetoreception by an unconventional photochemical mechanism

Myeloid lineage enhancers drive oncogene synergy in CEBPA/CSF3R mutant acute myeloid leukemia

Activation and repression of p21^WAF1/CIP1 transcription by RB binding proteins

In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes

Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia

Antibody decay, T cell immunity and breakthrough infections following two SARS-CoV-2 vaccine doses in inflammatory bowel disease patients treated with infliximab and vedolizumab

Cryptochrome mediates light-dependent magnetosensitivity in Drosophila

Evolution of genes and genomes on the Drosophila phylogeny

Proton Radiography Peers into Metal Solidification

Maintenance of pig brain function under extracorporeal pulsatile circulatory control (EPCC)

At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods

Mutant SETBP1 enhances NRAS-driven MAPK pathway activation to promote aggressive leukemia

Correction: Mutant SETBP1 enhances NRAS-driven MAPK pathway activation to promote aggressive leukemia

Morphodynamic evolution following sediment release from the world’s largest dam removal

Shared mechanisms between coronary heart disease and depression: findings from a large UK general population-based cohort

Real-time metabolic profiling of oesophageal tumours reveals an altered metabolic phenotype to different oxygen tensions and to treatment with Pyrazinib

Four consecutive yearly point-prevalence studies in Wales indicate lack of improvement in sepsis care on the wards

Delineating COVID-19 subgroups using routine clinical data identifies distinct in-hospital outcomes

ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19

Correction: Shared mechanisms between coronary heart disease and depression: findings from a large UK general population-based cohort

Author Correction: Delineating COVID-19 subgroups using routine clinical data identifies distinct in-hospital outcomes

Search

Quick links

Search

Filter By:

Search

Quick links