The intricacies of the structure and function of eosinophils are emerging within the context of eosinophilic diseases, in particular vasculitis. In this Review, the authors describe what is known about the biology of eosinophils and their potential to cause tissue and organ damage, with a focus on the role of these cells in eosinophilic granulomatosis with polyangiitis.
- Paneez Khoury
- Peter C. Grayson
- Amy D. Klion