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Showing 1–4 of 4 results
Advanced filters: Author: Amy Leonardson Clear advanced filters

  • The Somatic Mosaicism across Human Tissues Network aims to create a reference catalogue of somatic mosaicism across different tissues and cells within individuals.

    • Tim H. H. Coorens
    • Ji Won Oh
    • Yuqing Wang
    Reviews
    Nature
    Volume: 643, P: 47-59

  • In this paper gene expression is treated as a quantitative trait in both blood and adipose tissue, and associations between specific genetic loci and body mass index are identified using a molecular network approach.

    • Valur Emilsson
    • Gudmar Thorleifsson
    • Kari Stefansson
    Research
    Nature
    Volume: 452, P: 423-428

  • Standard approaches to identify the genetic changes that lead to disease are reversed by examination of genetic networks for perturbations that are associated with disease states, and following up candidate genes from there. This begins with three genes in mice that lead to obesity when mutated, demonstrating that complex genetic–environmental traits can be dissected with this new approach.

    • Yanqing Chen
    • Jun Zhu
    • Eric E. Schadt
    Research
    Nature
    Volume: 452, P: 429-435