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Advanced filters: Author: Anais Couvreux Clear advanced filters
  • Polycystin-2 (PC2) is an ion channel commonly found mutated in autosomal dominant polycystic kidney disease. Here Arhatte et al. identify transmembrane protein 33 (TMEM33) as a regulator of PC2 function at the endoplasmic reticulum, and find that deletion of TMEM33 protects mice from acute kidney injury.

    • Malika Arhatte
    • Gihan S. Gunaratne
    • Amanda Patel
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-16