Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–2 of 2 results
Advanced filters: Author: Anastasia Mylona Clear advanced filters

  • Phosphorylation at multiple sites is a major regulatory mechanism in cellular signalling. Here, the authors show that multisite phosphorylation of the c-JUN transcription factor by the JNK kinase exhibits intrinsic kinetics that allow a precise and timed regulation of the transcriptional output.

    • Christopher A. Waudby
    • Saul Alvarez-Teijeiro
    • Anastasia Mylona
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-12

  • Ras signalling activates the transcription factor c-Jun/AP-1, but the mechanism was unclear. Here, Chakraborty et al.describe a phosphorylation–ubiquitination cascade involving MSK1 and the E3 ubiquitin ligases Trim7 and RACO-1, which mediates c-Jun activation in Ras-driven lung tumorigenesis.

    • Atanu Chakraborty
    • Markus E. Diefenbacher
    • Axel Behrens
    Research
    Nature Communications
    Volume: 6, P: 1-12