Hypopituitarism, including growth hormone (GH) deficiency, is accompanied by increased morbidity and mortality. These factors may be due to the underlying disease and treatments such as surgery or radiotherapy, but can also arise from GH substitution therapy at nonphysiological doses. Nevertheless, emerging long-term data on GH replacement therapy now indicate benefits for bone health.
- Anders P. Jørgensen
- Jens Bollerslev
