Search

Benoit, Ganea et al. show that changes in axon initial segment (AIS) length in the prefrontal cortex of mice accompany fear learning and extinction, revealing AIS plasticity as a key feature of neuronal adaptation and memory formation.

Proximity effects in molecule/metal heterostructures offer a promising route to control magnetic properties. Here, the authors report a light-controlled proximity effect at a Co/C₆₀ interface, where laser-induced excitons in C₆₀ alter interfacial interactions, leading to a 60% quenching of the ferromagnetic resonance frequency of Co.

Clinical trials testing efficacy of novel HIV treatments rely on analytical treatment interruption (ATI). Using data from 24 prospective studies, the authors here show that the virus becomes detectable after around 16 days of ATI and that only 4% of individuals have sustained control of HIV, providing information for future clinical trial design.

A better-ventilated North Pacific could have reduced the carbon of water upwelled in the Southern Ocean, reducing outgassing and revealing a remote influence on Southern Ocean biogeochemistry in glacial times.

Itinerant magnetism in rhombohedral multilayer graphene shows a large excess entropy from magnetic fluctuations above its critical temperature—typically only associated with local moments—which implies the decoupling of charge and isospin degrees of freedom, and results in the isospin Pomeranchuk effect.

Helicity of photons is exploited for preferential emission direction and sorting of valley-polarized excitons is achieved at room temperature.

Moiré quasicrystals exhibit many exotic phenomena. Here, the authors report an acoustic moiré quasicrystal that not only achieves a localization-delocalization transition, but also enables wave propagation shifting from diffusion to canalization or localization.

Multi-exciton states may emerge in atomically thin transition metal dichalcogenides as a result of strong many-body interactions. Here, the authors report experimental evidence of four- and five-particle biexciton complexes in monolayer WSe₂ and their electrical control.

This study presents the evolution of the dust attenuation curve in galaxies over cosmic time, suggesting that dust attenuation at early times is dominated by large grains from supernovae. The study also reports an ultraviolet bump in a source at redshift z ≈ 7.5.

The use of gaseous sulfuryl fluoride in sulfur(VI) fluoride exchange reactions is a challenge. Now, a flow set-up for the on-demand generation and onward reaction of sulfuryl fluoride, from sulfuryl chloride, is reported. The process produces fluorosulfate and sulfamoyl fluoride analogues of small molecules, peptides and proteins.

A modularized open-source pipeline for invasive brain signal decoding bridges the gap between closed-loop neuromodulation and clinical brain–computer interface approaches in a large patient cohort.

The social exposome—lifelong social and economic adversity—can shape brain health and dementia risk. Here, the authors show that an adverse social exposome is linked to poorer clinical, cognitive, and brain changes in Latin American older adults.

Analysis of earthquakes from the last two millennia indicate two potential supercycles along the East Anatolian Fault. Within each supercycle, seismic ruptures originated in the northeast and progressively spread southwestward with an increasing number of earthquakes.

Non-Hermitian physics enables dynamic control of optical behaviour in real time, such as reflectionless scattering modes, which have now been demonstrated in a chaotic photonic microcavity.

At the quantum limit, vacuum fluctuations determine the precision with which a signal can be measured. In this work the authors use a technique known as squeezing to greatly reduce the vacuum fluctuation noise present at microwave frequencies.

Tumor-associated macrophages (TAMs) play multifaceted roles in establishing an immunosuppressive tumor microenvironment. Sica and colleagues find that macrophage-intrinsic complement signaling initiates a pathway leading to the induction of highly tumorigenic TAMs.

The charge-density-wave state in RbV₃Sb₅ can be optically manipulated by applying linearly polarized light along high-symmetry directions, which demonstrates the potential of light as a control knob to manipulate complex quantum phenomena in correlated materials.

Replica symmetry breaking describes identical copies of a randomly interacting system exhibiting different dynamics. Here, Pierangeli et al. observe this critical phenomenon in the optical wave propagation inside a disordered nonlinear waveguide.

Gradients of cell recognition molecules wire a sensorimotor interface in Drosophila.

The ability to assemble weakly-interacting subsystems is a prerequisite for implementing quantum-information processing. In recent years, molecular nanomagnets have been proposed as suitable candidates for qubit encoding and manipulation, with antiferromagnetic Cr₇Ni rings of particular interest. It has now been shown that such rings can be chemically linked to each other and the coupling between their spins tuned through the choice of chemical linker.

A subpopulation of astrocytes selectively expresses synaptic-like glutamate-release machinery, actively secretes the transmitter and is localized to discrete sites in the hippocampus.

Experimental observations and theoretical analysis provide evidence that the spin polarization of the spin-spiral type II multiferroic NiI₂ exhibits p-wave magnetism and its spin chirality is related to ferroelectric polarization, which can be electrically controlled. 

Advancements in bioelectronic therapies offer new hope for treating various disorders. Here, the authors present an accurate, subject-specific model of vagus nerve stimulation for enhancing efficacy and reducing side effects.

Device-independent self-testing is an approach that allows a complete certification of an unknown quantum state, simply by inspecting outcomes of measurements. Here, the authors demonstrate that any pure bipartite entangled state can be self-tested.

Controlling the coherent evolution of cavity quantum electrodynamics systems is key for future quantum networks. Here Pagliano et al.demonstrate dynamic control of the coupling of a single exciton to a photonic micro-resonator using electrical tuning of the exciton energy in a photonic crystal cavity diode.

Interlayer excitons in bilayer MoS₂ exhibit both a high oscillator strength and highly tunable energies in an applied electric field.

A Greenland ice core reveals that Arctic atmospheric nitrate since the Industrial Revolution has been controlled not only by NOx emissions but also by atmospheric acidity, affecting its gas-particle partitioning, lifetime, and long-range transport.

Every spring, Bogong moths use the starry night sky as a compass to navigate up to 1,000 km towards their alpine migratory goal.

One argument for conserving biological diversity is that it delivers beneficial ecosystem services. However, Kleijn et al.show that the economic benefits of crop pollination are delivered by only a small subset of relatively common species, arguing that threatened species should be considered separately.

Researchers created a periodically poled van der Waals semiconductor (3R-MoS₂) and achieved a macroscopic frequency conversion efficiency of 0.03% over a thickness of 3.4 μm. The quasi-phase-matched second harmonic signal surpasses the usual quadratic enhancement by 50% and broadband generation of photon pairs at telecom wavelength is demonstrated with a coincidence-to-accidental ratio of 638 ± 75.

Abbasi et al. evaluate the value of source data verification, a costly but traditional element of clinical trials. They find it is largely redundant when used with a systematic strategy to promote efficient and accurate data capture, monitoring, and safety in a phase II platform trial.

Trial Registration: https://clinicaltrials.gov/study/NCT04488081

Spatial transcriptomic approaches often lack single-cell resolution and read coverage. Here, we introduce spatial ISOform sequencing (Spl-ISO-Seq) which optimizes the capture of long, exonic molecules. This technology reveals developmentally-regulated cell-type and region-specific splicing patterns.

Ovonic threshold switching between high-resistive and conductive states in chalcogenide alloys is crucial for phase change memories and selector elements, yet its voltage dependence on field polarity remains underexplored. Here, the authors elucidate this phenomenon using electrical measurements, numerical simulations based on Technology Computer Aided Design, and DFT calculations, proposing a Graded Band Gap model that enhances memory design by predicting programming window characteristics.

Coherent quantum control of a single ¹²³Sb nucleus using electric fields produced within a silicon nanoelectronic device is demonstrated experimentally, validating a concept predicted theoretically in 1961.

A critical factor in the theoretical modelling of nanoscale metal halide perovskites is the system size. Here the authors demonstrate the effect on the band gap of FAPbI₃ via octahedra tilting and dipole moments using large-scale ab initio simulations.

Introducing local, nanoscopic ferromagnetic regions in a synthetic antiferromagnet racetrack can help to mitigate the trade-off between energy efficiency and thermal stability in magnetic domain-wall-based devices.

Different motor symptoms respond variably to deep brain stimulation in Parkinson’s Disease. Rajamani et al. suggest that this variability may be due to tremor, bradykinesia, rigidity, and axial symptoms being associated with a gradient of brain circuits.

This study explores the dynamics of adolescent depression through the lens of network temperature, a novel concept in psychological symptom networks. Researchers observed a decrease in network temperature across adolescence, indicating increased stability and decreased variability of depressive symptoms as adolescents age and with distinct patterns between sexes. This work emphasizes the importance of understanding network dynamics over static measures, offering new insights into the stability and variability of depression symptoms.

The cGAS–STING pathway has a central role in the pathogenesis of severe COVID-19 by driving the increase in type I interferons that occurs in the later stages of SARS-CoV-2 infection.

The phenomenon of circumferential faceting in multiwalled nanotubes of general chirality and identity is rationalized in terms of interwall registry patterns between adjacent layers of curved hexagonal lattices.

The authors report Bose–Einstein condensation of a two-magnon bound state in Na₂BaNi(PO₄)₂. This should stimulate further work on these types of geometrically frustrated materials.

Over the last 15 years, the content of Nature Physics has covered an enormous breadth of subjects at the forefront of physics. The journal’s past and present editors recount their favourite papers and what made chaperoning them to publication special.

Cryogenic-electron microscopy is used to determine the structure of TFEB as presented to mTORC1 for phosphorylation and an explanation is found for the strong dependence of TFEB phosphorylation on FLCN and the RagC GDP state.

Tactile sensing is needed for robots to physically interact with humans in daily living and in the workplace. A scientific challenge in robotics is how to simultaneously detect contact location and intensity. The authors describe a large-area sensing skin for robotic system applications, specifically for human–machine interactions.

Mode-selective vibrational excitations can be used to transiently induce a range of phenomena in strongly correlated states of matter. It is now shown that by exciting apical oxygen distortions in the cuprate system YBa₂Cu₃O_6.5, an unusual photoconductive effect is induced both at low and at high temperatures.

In this work, authors propose a synergistic approach combining state-of-the-art deterministic forecasting model with artificial intelligence for predicting lightning occurrences. The strategy shows efficient predictive capabilities at medium-range forecast horizons.