Sepsis is the most common and severe cause of morbidity and mortality among critically ill patients. Acute kidney injury (AKI) can complicate sepsis, with a linear relationship between the severity of kidney damage and patient prognosis. In this Review, the authors describe currently available interventions for sepsis-related AKI. In addition, they discuss preventive methods, pharmacological support and extracorporeal blood purification for septic AKI.
- Zaccaria Ricci
- Andrea Polito
- Claudio Ronco