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Showing 1–2 of 2 results
Advanced filters: Author: Andrea Nieto-Aliseda Clear advanced filters

  • Here the authors uncover p53’s role as the master regulator of spatio-temporal genome organization. p53 controls the expression of 340 distal genes through newly formed and pre-existing loops between p53-bound enhancers and promoters.

    • François Serra
    • Andrea Nieto-Aliseda
    • Biola M. Javierre
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-19

  • Here the authors present the low input capture Hi-C (liCHi-C) method, a cost-effective, flexible method to map and robustly compare promoter interactomes at high resolution. liCHi-C identifies new disease-associated genes and structural variants to ultimately illuminate their pathogenic effects.

    • Laureano Tomás-Daza
    • Llorenç Rovirosa
    • Biola M. Javierre
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-16