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Advanced filters: Author: Andrea Olland Clear advanced filters

  • An NNMT inhibitor reduces tumour burden and metastasis in multiple mouse cancer models and restores immune checkpoint blockade efficacy by decreasing cancer-associated-fibroblast-mediated recruitment of myeloid-derived suppressor cells and reinvigorating CD8+ T cell activation.

    • Janna Heide
    • Agnes J. Bilecz
    • Ernst Lengyel
    Research
    Nature
    Volume: 645, P: 1051-1059