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Showing 1–14 of 14 results
Advanced filters: Author: Andrea Ravasio Clear advanced filters

  • Observations of a fast X-ray transient reveal that it is a gamma-ray-burst explosion from a very distant galaxy that emits light with the wavelength necessary to drive cosmic reionization, the last major phase change in the history of the Universe.

    • Andrew J. Levan
    • Peter G. Jonker
    • Tayyaba Zafar
    Research
    Nature Astronomy
    Volume: 9, P: 1375-1386

  • Epithelial wound closure proceeds through both crawling into the wound and by constricting an actomyosin cable in a so-called purse-string mechanism. Here the authors show that the two mechanisms are mechanically coupled and the curvature of the wound regulates the overall dynamics of wound closure.

    • Andrea Ravasio
    • Ibrahim Cheddadi
    • Benoit Ladoux
    ResearchOpen Access
    Nature Communications
    Volume: 6, P: 1-13

  • Observations from the JWST of the second brightest GRB ever detected, GRB 230307A, indicate that it belongs to the class of long-duration GRBs resulting from compact object mergers, with the decay of lanthanides powering the longlasting optical and infrared emission.

    • Andrew J. Levan
    • Benjamin P. Gompertz
    • David Alexander Kann
    ResearchOpen Access
    Nature
    Volume: 626, P: 737-741

  • Systemic light chain amyloidosis (AL) is caused by the production of toxic light chains and can be fatal, yet effective treatments are often not possible due to delayed diagnosis. Here the authors show that a machine learning platform analyzing light chain somatic mutations allows the prediction of light chain toxicity to serve as a possible tool for early diagnosis of AL.

    • Maura Garofalo
    • Luca Piccoli
    • Andrea Cavalli
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-10

  • A possible kilonova associated with a nearby, long-duration gamma-ray burst suggests that gamma-ray bursts with long and complex light curves can be spawned from the merger of two compact objects, contrary to the established gamma-ray burst paradigm.

    • Jillian C. Rastinejad
    • Benjamin P. Gompertz
    • Christina C. Thöne
    Research
    Nature
    Volume: 612, P: 223-227

  • Caloric restriction (CR) has been demonstrated to have a role in tumour growth and therapy response but its effects on cancer stem cells are less known. Here, in Acute Promyelocytic Leukemia, the authors show that despite initial anti-tumour effect, CR drives the selection of leukaemia-initiating cells resulting in relapse which could be prevented by ablation of LSD1.

    • Rani Pallavi
    • Elena Gatti
    • Pier Giuseppe Pelicci
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-18

  • Ravasio et al. develop an assay to quantify the clustering of Eph receptor EphA2 upon ligand binding, based on the scoring of single cells. They discover that clustering phenotype predicts cell and population migration potential in cancer cells and reflects Eph associated gene expression profiles in cancer cell lines.

    • Andrea Ravasio
    • Myint Z. Myaing
    • Virgile Viasnoff
    ResearchOpen Access
    Communications Biology
    Volume: 3, P: 1-12

  • Bertocchi and colleagues describe the organization of cadherin-based adhesions using super-resolution microscopy. They find that α-catenin is important for vinculin localization and observe a conformational change in vinculin following its activation.

    • Cristina Bertocchi
    • Yilin Wang
    • Pakorn Kanchanawong
    Research
    Nature Cell Biology
    Volume: 19, P: 28-37