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Showing 1–3 of 3 results
Advanced filters: Author: Andreas Metousis Clear advanced filters
  • Cell-type-resolved spatial proteomics of the skin from patients with toxic epidermal necrolysis reveals that it is driven by JAK/STAT signaling, leading to successful treatment of this potentially fatal condition in patients using JAK inhibitors.

    • Thierry M. Nordmann
    • Holly Anderton
    • Matthias Mann
    ResearchOpen Access
    Nature
    Volume: 635, P: 1001-1009
  • High-resolution spatial proteomics were used to map molecular events during hepatocyte stress in pseudotime across all fibrosis stages, recapitulating known disease progression markers and revealing early peroxisomal activation and late-stage proteotoxic phenotypes.

    • Florian A. Rosenberger
    • Sophia C. Mädler
    • Matthias Mann
    ResearchOpen Access
    Nature
    Volume: 642, P: 484-491