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Advanced filters: Author: Andreas Zuckermann Clear advanced filters

Investigation of a global mouse methylome atlas reveals subtype-specific copy number alterations in pediatric cancer models

DNA methylation and copy number variant analyses across a large number of genetic mouse models of pediatric brain tumors reveal subtype-specific molecular alterations shared with the corresponding human diseases.

Melanie Schoof
Tuyu Zheng
Marc Zuckermann
ResearchOpen Access11 Dec 2025
Nature Genetics

Volume: 58, P: 143-156
Heterologous vector versus homologous mRNA COVID-19 booster vaccination in non-seroconverted immunosuppressed patients: a randomized controlled trial

Optimizing COVID-19 vaccination strategies for patients under immunosuppressive medication is of high importance. In this clinical trial including non-seroconverted immunosuppressed patients, a homologous mRNA booster vaccination resulted in higher seroconversion rate than a switch to a vector-based vaccine.

Daniel Mrak
Daniela Sieghart
Michael Bonelli
ResearchOpen Access12 Sept 2022
Nature Communications

Volume: 13, P: 1-9
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma

Stefan Pfister and the ICGC PedBrain Tumor Project report whole-genome sequencing of 96 pilocytic astrocytomas. They identify recurrent activating mutations in FGFR1 and PTPN11 and novel NTRK2 fusion genes.

David T W Jones
Barbara Hutter
Stefan M Pfister
Research30 Jun 2013
Nature Genetics

Volume: 45, P: 927-932

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