Nature Search

SARS-CoV-2 infection of human pluripotent stem cell-derived vascular cells reveals smooth muscle cells as key mediators of vascular pathology during infection

This study uses a novel vascular model with human induced pluripotent stem cell-derived endothelial cells, pericytes, and smooth muscle cells to explore the vascular complications associated with SARS-CoV-2. It reveals that smooth muscle cells as the primary sites of infection and inflammation.

Alexsia Richards
Andrew S. Khalil
Rudolf Jaenisch
ResearchOpen Access30 Dec 2024
Nature Communications

Volume: 15, P: 1-17
Correction: Corrigendum: The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons

Ingo Braasch
Andrew R Gehrke
John H Postlethwait
Amendments and Corrections27 May 2016
Nature Genetics

Volume: 48, P: 700
Organoid culture promotes dedifferentiation of mouse myoblasts into stem cells capable of complete muscle regeneration

Mouse stem cells that regenerate muscle are derived by organoid dedifferentiation of myoblasts.

Feodor D. Price
Mark N. Matyas
Lee L. Rubin
ResearchOpen Access11 Sept 2024
Nature Biotechnology

Volume: 43, P: 889-903
Capturing sequence diversity in metagenomes with comprehensive and scalable probe design

A sensitive method to analyze metagenomes, CATCH, enables detection and characterization of diverse viral sequences, including the 356 viruses known to infect humans.

Hayden C. Metsky
Katherine J. Siddle
Christian B. Matranga
Research04 Feb 2019
Nature Biotechnology

Volume: 37, P: 160-168
Zika virus evolution and spread in the Americas

One hundred and ten Zika virus genomes from ten countries and territories involved in the Zika virus epidemic reveal rapid expansion of the epidemic within Brazil and multiple introductions to other regions.

Hayden C. Metsky
Christian B. Matranga
Pardis C. Sabeti
Research24 May 2017
Nature

Volume: 546, P: 411-415
Digits and fin rays share common developmental histories

Hoxa- and Hoxd-deficient zebrafish generated using Crispr/Cas with fate mapping have reduced fin rays and increased endochondral elements, establishing homology between the developmental programs that create fin rays and the wrists and digits of mammals.

Tetsuya Nakamura
Andrew R. Gehrke
Neil H. Shubin
Research17 Aug 2016
Nature

Volume: 537, P: 225-228
The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons

Ingo Braasch, John Postlethwait and colleagues report the genome of the spotted gar (Lepisosteus oculatus), whose lineage diverged from teleosts before genome duplication. Their data provide insights into the evolution of genes involved in immunity, mineralization and development and facilitate the comparison of cis-regulatory elements between teleosts and humans.

Ingo Braasch
Andrew R Gehrke
John H Postlethwait
ResearchOpen Access07 Mar 2016
Nature Genetics

Volume: 48, P: 427-437
The IMPACT framework and implementation for accessible in silico clinical phenotyping in the digital era

Andrew Wen
Huan He
Hongfang Liu
ReviewsOpen Access21 Jul 2023
npj Digital Medicine

Volume: 6, P: 1-8

Search

Filter By:

Search

Quick links