Nature Search

A Lassa virus mRNA vaccine confers protection but does not require neutralizing antibody in a guinea pig model of infection

Lassa virus infections in humans can result in severe disease, including hemorrhagic fever. Here the authors describe an mRNA-based Lassa virus vaccine that shows protection without requirement for neutralizing antibody in a guinea pig model of infection.

Adam J. Ronk
Nicole M. Lloyd
Alexander Bukreyev
ResearchOpen Access12 Sept 2023
Nature Communications

Volume: 14, P: 1-13
In vivo topical gene therapy for recessive dystrophic epidermolysis bullosa: a phase 1 and 2 trial

Preclinical data and results from a phase 1 and 2 trial demonstrate preliminary safety and efficacy of topical gene therapy for recessive dystrophic epidermolysis bullosa

Irina Gurevich
Pooja Agarwal
M. Peter Marinkovich
ResearchOpen Access28 Mar 2022
Nature Medicine

Volume: 28, P: 780-788
Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis

Experimental deletion of the furin cleavage site of the SARS-CoV-2 spike protein highlights an important role for this site in infection and the need to consider this site when evaluating the neutralization activities of antibodies.

Bryan A. Johnson
Xuping Xie
Vineet D. Menachery
Research25 Jan 2021
Nature

Volume: 591, P: 293-299
Megahertz pulse trains enable multi-hit serial femtosecond crystallography experiments at X-ray free electron lasers

Free-electron lasers are capable of high repetition rates and it is assumed that protein crystals often do not survive the first X-ray pulse. Here the authors address these issues with a demonstration of multi-hit serial crystallography in which multiple FEL pulses interact with the sample without destroying it.

Susannah Holmes
Henry J. Kirkwood
Connie Darmanin
ResearchOpen Access11 Aug 2022
Nature Communications

Volume: 13, P: 1-13
Life on a Mesoarchean marine shelf – insights from the world’s oldest known granular iron formation

Albertus J. B. Smith
Nicolas J. Beukes
Stanley M. Awramik
ResearchOpen Access29 Jun 2020
Scientific Reports

Volume: 10, P: 1-8
NBEAL2 is mutated in gray platelet syndrome and is required for biogenesis of platelet α-granules

Meral Gunay-Aygun and colleagues report that NBEAL2 is mutated in gray platelet syndrome (GPS). GPS is a recessive platelet disorder that can lead to severe bleeding.

Meral Gunay-Aygun
Tzipora C Falik-Zaccai
William A Gahl
Research17 Jul 2011
Nature Genetics

Volume: 43, P: 732-734
Artificial intelligence in epilepsy — applications and pathways to the clinic

Integration of artificial intelligence into epilepsy management could revolutionize diagnosis and treatment. In this Review, the authors provide an overview of artificial intelligence applications that have been developed in epilepsy and discuss challenges that must be addressed to successfully integrate artificial intelligence into clinical practice.

Alfredo Lucas
Andrew Revell
Kathryn A. Davis
Reviews08 May 2024
Nature Reviews Neurology

Volume: 20, P: 319-336
Novel deletions affecting the MEG3-DMR provide further evidence for a hierarchical regulation of imprinting in 14q32

Jasmin Beygo
Miriam Elbracht
Thomas Eggermann
Research07 May 2014
European Journal of Human Genetics

Volume: 23, P: 180-188
AI is a viable alternative to high throughput screening: a 318-target study

Izhar Wallach
Denzil Bernard
Abraham Heifets
ResearchOpen Access02 Apr 2024
Scientific Reports

Volume: 14, P: 1-16
Dyke apertures record stress accumulation during sustained volcanism

Samuel T. Thiele
Alexander R. Cruden
Jonas Köpping
ResearchOpen Access15 Oct 2020
Scientific Reports

Volume: 10, P: 1-9
Monitoring ultrafast metallization in LaCoO₃ with femtosecond soft x-ray spectroscopy

The properties of strongly correlated materials have been successfully studied via ultrafast dynamics methods. The authors present combined experimental and theoretical results of photo-excitation of LaCoO₃ to probe the mechanisms at play behind the semiconductor-to-metal transition at high temperature.

Manuel Izquierdo
Michael Karolak
Serguei L. Molodtsov
ResearchOpen Access18 Jan 2019
Communications Physics

Volume: 2, P: 1-8
Author Correction: AI is a viable alternative to high throughput screening: a 318-target study

Izhar Wallach
Denzil Bernard
Ellie Giles
Amendments and CorrectionsOpen Access16 Sept 2024
Scientific Reports

Volume: 14, P: 1-2

Search

A Lassa virus mRNA vaccine confers protection but does not require neutralizing antibody in a guinea pig model of infection

In vivo topical gene therapy for recessive dystrophic epidermolysis bullosa: a phase 1 and 2 trial

Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis

Megahertz pulse trains enable multi-hit serial femtosecond crystallography experiments at X-ray free electron lasers

Life on a Mesoarchean marine shelf – insights from the world’s oldest known granular iron formation

NBEAL2 is mutated in gray platelet syndrome and is required for biogenesis of platelet α-granules

Artificial intelligence in epilepsy — applications and pathways to the clinic

Novel deletions affecting the MEG3-DMR provide further evidence for a hierarchical regulation of imprinting in 14q32

AI is a viable alternative to high throughput screening: a 318-target study

Dyke apertures record stress accumulation during sustained volcanism

Monitoring ultrafast metallization in LaCoO₃ with femtosecond soft x-ray spectroscopy

Author Correction: AI is a viable alternative to high throughput screening: a 318-target study

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