[18F]6-fluoro-l-DOPA ([18F]FDOPA) is used for diagnostic PET imaging. Using this protocol, radiofluorination of the electron-rich catechol ring can be achieved in the presence of the amino acid group via Cu-mediated fluorination of a pinacol boronate precursor.
- Andrew V. Mossine
- Sean S. Tanzey
- Peter J. H. Scott