Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–7 of 7 results
Advanced filters: Author: Angera H Kuo Clear advanced filters

  • Two studies show that circulating tumor cells from breast cancer patients give rise to metastases in mice.

    • Angera H Kuo
    • Michael F Clarke
    News & Views
    Nature Biotechnology
    Volume: 31, P: 504-505

  • Super-enhancers (SEs) are big DNA regions regulating the transcription of oncogenes. Here the authors identify two SE regions regulating the expression of CD47, a protein expressed by cancer cells to avoid phagocytosis by macrophages, thus suggesting a potential mechanism of immune surveillance escape.

    • Paola A. Betancur
    • Brian J. Abraham
    • Irving L. Weissman
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-14

  • An analysis of somatic tissues derived from mouse models of Down’s syndrome shows reduced self-renewal capacities in various cell types, with these defects partially dependent on triplication of the Usp16 gene; overexpression and knockout studies in human cells shows that USP16 has a role in Down’s syndrome-related proliferation defects, making this gene an attractive option for further study.

    • Maddalena Adorno
    • Shaheen Sikandar
    • Michael F. Clarke
    Research
    Nature
    Volume: 501, P: 380-384

  • The contribution of EMT in mammary gland homeostasis and human breast cancer is still unclear. Here, using in vivo lineage tracing and breast cancer PDXs the authors demonstrate that the repopulating capacity in normal mammary epithelial cells and tumorigenic capacity in breast cancer is independent of expression of EMT-associated genes.

    • Shaheen S. Sikandar
    • Angera H. Kuo
    • Michael F. Clarke
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-9