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Communications Biology (2)
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Advanced filters: Author: Anhadvir Singh Clear advanced filters

Evolution of iGluR ligand specificity, polyamine regulation, and ion selectivity inferred from a placozoan epsilon receptor

The authors generated a species-guided phylogeny of eukaryotic iGluRs, alongside a focused analysis of iGluR homologues from the early-branching invertebrate phylum Placozoa.

Anhadvir Singh
Boris S. Zhorov
Adriano Senatore
ResearchOpen Access03 Jul 2025
Communications Biology

Volume: 8, P: 1-23
Mint/X11 PDZ domains from non-bilaterian animals recognize and bind Ca_V2 calcium channel C-termini in vitro

Alicia N. Harracksingh
Anhadvir Singh
Adriano Senatore
ResearchOpen Access16 Sept 2024
Scientific Reports

Volume: 14, P: 1-27
Function and phylogeny support the independent evolution of an ASIC-like Deg/ENaC channel in the Placozoa

The non-bilaterian Trichoplax adhaerens has a proton-activated Deg/ENaC channel with ASIC-like biophysical properties but distinct determinants for proton gating. Phylogenetic evidence for the existence of Deg/ENaC channels outside of animals is also provided.

Wassim Elkhatib
Luis A. Yanez-Guerra
Adriano Senatore
ResearchOpen Access18 Sept 2023
Communications Biology

Volume: 6, P: 1-20

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