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Advanced filters: Author: Anika Freise Clear advanced filters

  • Actin polymerization in lamellipodia of cells is regulated by the Arp2/3 complex and FMNL family formins. Here the authors show that both FMNL2 and FMNL3 contribute to lamellipodium protrusion and structure, and abolishing FMNL2/3 reduces protrusion force generation and migration, without affecting Arp2/3 incorporation.

    • Frieda Kage
    • Moritz Winterhoff
    • Klemens Rottner
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-16