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Showing 1–3 of 3 results
Advanced filters: Author: Anja Forche Clear advanced filters

  • Candida albicans is a prominent human fungal pathogen that until now was thought to be an obligate diploid; here it is shown that C. albicans can form viable haploids, that these haploids are able to mate to form heterozygous diploids, and that haploids and their auto-diploids are significantly less fit in vitro and in vivo than heterozygous progenitors or diploids formed by haploid mating pairs.

    • Meleah A. Hickman
    • Guisheng Zeng
    • Judith Berman
    Research
    Nature
    Volume: 494, P: 55-59

  • Candida species are the most common cause of opportunistic fungal infection worldwide. Here, the genomes of six Candida species are sequenced and compared with each other and with related pathogens and non-pathogens; providing insight into the genetic features that underlie the diversity of Candida biology, including pathogenesis and the architecture of mating and meiotic processes.

    • Geraldine Butler
    • Matthew D. Rasmussen
    • Christina A. Cuomo
    ResearchOpen Access
    Nature
    Volume: 459, P: 657-662