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Showing 1–2 of 2 results
Advanced filters: Author: Anja Waizenegger Clear advanced filters

  • Smc5/6, part of the structural maintenance of chromosomes (SMC) family, plays roles in genome structural integrity. Here the authors reveal that Smc5/6 acts jointly with Top3 within the STR complex to mediate DNA replication completion at genomic natural pausing sites (NPSs).

    • Sumedha Agashe
    • Chinnu Rose Joseph
    • Dana Branzei
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-15

  • Mus81-Mms4 endonuclease is critical for processing various DNA recombination structures. Here the authors uncover a regulatory mechanism of the endonuclease via posttranslational modifications involving SUMOylation and ubiquitylation that impact on genome integrity.

    • Anja Waizenegger
    • Madhusoodanan Urulangodi
    • Dana Branzei
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-14