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Showing 1–8 of 8 results
Advanced filters: Author: Anjon Audhya Clear advanced filters

  • A fusion of cutting-edge research in cell biology, developmental biology and immunology made the recent workshop on Membrane Dynamics in Endocytosis an outstanding success. Members of an increasingly diverse community converged upon the small town of Sant Feliu de Guixols on the coast of Spain, between September 17–22, 2005, to discuss common themes emerging from their studies on membrane transport. Organized by Margaret Robinson (Cambridge, UK) and Howard Riezman (Geneva, Switzerland), the meeting covered diverse topics that highlighted essential roles for endocytosis during cell growth, development and parasitic invasion.

    • Barth D. Grant
    • Anjon Audhya
    News & Views
    Nature Cell Biology
    Volume: 7, P: 1151-1154

  • Movement of secretory cargoes from the endoplasmic reticulum relies on the COPII protein complex. Here, authors combine gene editing technology with state-of-the-art fluorescence microscopy to define the native dynamics of COPII recruitment at ER subdomains for the first time.

    • William Kasberg
    • Peter Luong
    • Anjon Audhya
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-13

  • During the oocyte-to-embryo transition in C. elegans, multivesicular endosomes (MVEs) are formed rapidly. Using live imaging and electron microscopy, the authors here show that the ESCRT-III subunit Ist1 is required for normal MVE biogenesis in the early C. elegans embryo.

    • E. B. Frankel
    • Raakhee Shankar
    • Anjon Audhya
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-13

  • TFG-1 is identified as a regulator of COPII coat assembly that interacts with SEC-16 to control protein exit from the endoplasmic reticulum. TFG–kinase fusion proteins have been detected in some cancers and might promote oncogenesis by prematurely phosphorylating target substrates as they exit the endoplasmic reticulum.

    • Kristen Witte
    • Amber L. Schuh
    • Anjon Audhya
    Research
    Nature Cell Biology
    Volume: 13, P: 550-558

  • Mad1 is well characterised for its function in mitosis. Here, the authors describe an interphase role for Mad1 in tumour promotion in which it destabilises p53 by localizing to PML nuclear bodies and displacing MDM2 from the PML-MDM2 complex.

    • Jun Wan
    • Samuel Block
    • Beth A. Weaver
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-14

  • The C.elegans anchor cell is a model for cellular invasion through the basement membrane. Now netrin (UNC-6) is found to polarize the actin regulators Ena/VASP and PtdIns (4,5)P2 towards the basement membrane to promote anchor cell invasion.

    • Joshua W. Ziel
    • Elliott J. Hagedorn
    • David R. Sherwood
    Research
    Nature Cell Biology
    Volume: 11, P: 183-189