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Showing 1–5 of 5 results
Advanced filters: Author: Anke Mueller-Fahrnow Clear advanced filters

  • The Structural Genomics Consortium (SGC) and its clinical, industry and disease-foundation partners are launching open-source preclinical translational medicine studies.

    • Aled M. Edwards
    • Cheryl H. Arrowsmith
    • L. Trevor Young
    Comments & Opinion
    Nature Reviews Drug Discovery
    Volume: 14, P: 149-150

  • Target 2035 aims to develop a potent and selective pharmacological modulator for every human protein by 2035 with the results made publicly available. This Roadmap article sets out how that will be achieved.

    • Aled M. Edwards
    • Dafydd R. Owen
    • Suzanne Ackloo
    Reviews
    Nature Reviews Chemistry
    Volume: 9, P: 634-645

  • Chemical probes are powerful reagents with increasing impacts on biomedical research. However, probes of poor quality or that are used incorrectly generate misleading results. To help address these shortcomings, we will create a community-driven wiki resource to improve quality and convey current best practice.

    • Cheryl H Arrowsmith
    • James E Audia
    • William J Zuercher
    Comments & Opinion
    Nature Chemical Biology
    Volume: 11, P: 536-541

  • A genetics-led translational approach integrating functional genomic predictors, knowledge of network connectivity and immune ontologies defines the drug target prioritization landscape for 30 immune traits at the gene and pathway level.

    • Hai Fang
    • Georg Beckmann
    • Julian C. Knight
    Research
    Nature Genetics
    Volume: 51, P: 1082-1091