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Showing 1–2 of 2 results
Advanced filters: Author: Ankit Jambusaria Clear advanced filters
  • Endothelial cell regeneration is essential for blood vessels to recover from inflammation-induced injury. Here Liu et al. show that the transcription factor Sox17 is required for endothelial regeneration following endotoxemia, and that delivery of a transgene expressing Sox17 to lung endothelial cells enhances recovery after injury.

    • Menglin Liu
    • Lianghui Zhang
    • Asrar B. Malik
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-14
  • Endothelial tissues must have intact barrier function, but this may be disrupted during inflammation. Here, the authors show that the mitochondrial protein Mitofusin-2 stabilizes cell–cell adherens junctions in endothelial cells during homeostasis and binds the transcriptional activator β-catenin upon inflammatory stimulation.

    • Young-Mee Kim
    • Sarah Krantz
    • Jalees Rehman
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-17