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Showing 1–7 of 7 results
Advanced filters: Author: Ankit Malik Clear advanced filters

  • Here Ramanan and colleagues provide an analysis of mammary T cells during late pregnancy and lactation. This revealed an increase in intraepithelial lymphocytes in the lactating mammary gland, which was driven by thymic and intestinal inputs and was sensitive to changes in the microbiota

    • Abigail Jaquish
    • Eleni Phung
    • Deepshika Ramanan
    Research
    Nature Immunology
    Volume: 26, P: 1411-1422

  • Endothelial cell regeneration is essential for blood vessels to recover from inflammation-induced injury. Here Liu et al. show that the transcription factor Sox17 is required for endothelial regeneration following endotoxemia, and that delivery of a transgene expressing Sox17 to lung endothelial cells enhances recovery after injury.

    • Menglin Liu
    • Lianghui Zhang
    • Asrar B. Malik
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-14

  • IFNγ signalling in epithelial cells promotes antigen presentation that confers intra-epithelial T cells the ability to limit extracellular ATP and consequent NLRP3 inflammasome activation, controlling pathogenic transformation of CD4+ T cells that promotes colitis and colorectal cancer in mouse models.

    • Ankit Malik
    • Deepika Sharma
    • Bana Jabri
    Research
    Nature
    Volume: 623, P: 1044-1052

  • Sepsis due to multidrug resistant pathogens is the most common cause of death in intensive care units. Here, the authors report that fecal microbiota transplant (FMT) can rescue mice from lethal sepsis of pathogens isolated from stool of a critically ill patient and show that FMT reverses the immunosuppressive effect induced by the pathogen community.

    • Sangman M. Kim
    • Jennifer R. DeFazio
    • John C. Alverdy
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-11

  • The rich ethnolinguistic and sociocultural differences that exist in India offers a unique opportunity to study human diversity. With the whole genomes of 10,000 healthy and unrelated Indians from 83 populations, the GenomeIndia project captures the genetic diversity of one of the highly underrepresented populations in the global genomics landscape.

    • Chandrika Bhattacharyya
    • Krithika Subramanian
    • Bratati Kahali
    Comments & Opinion
    Nature Genetics
    Volume: 57, P: 767-773