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Showing 1–4 of 4 results
Advanced filters: Author: Anna Czarkwiani Clear advanced filters

  • This study identifies three conserved shadow enhancers (T3, C, I) regulating notochord expression of Brachyury across vertebrates using genomic data, transgenic assays, and enhancer knockouts, which are critical for vertebrate notochord development.

    • Cassie L. Kemmler
    • Jana Smolikova
    • Alexa Burger
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-18

  • Numerous tissues are derived from the lateral plate mesoderm (LPM) but how this is specified is unclear. Here, the authors identify a pan-LPM reporter activity found in the zebrafish draculin (drl) gene that also shows transgenic activity in LPM-corresponding territories of several chordates, including chicken, axolotl, lamprey, Ciona, and amphioxus.

    • Karin D. Prummel
    • Christopher Hess
    • Christian Mosimann
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-15