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Showing 1–2 of 2 results
Advanced filters: Author: Anna L. Valkov Clear advanced filters

  • Intracellular pathogens hijack host gene expression to subvert cellular processes. Here, the authors show that Legionella pneumophila’s PieF effector inhibits the human CCR4-NOT deadenylation machinery, impacting mRNA poly(A) tail shortening and impairing cell division.

    • Yevgen Levdansky
    • Justin C. Deme
    • Eugene Valkov
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-11

  • mRNAs are continually degraded in the cytoplasm through a process known as bulk mRNA decay. Here the authors show a role of uridylation in directing 5’ to 3’ mRNA decay pathway in fission yeast.

    • Maciej Grochowski
    • Lidia Lipińska-Zubrycka
    • Michał Małecki
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-12