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Showing 1–5 of 5 results
Advanced filters: Author: Anna Maria Gerdina Pasmooij Clear advanced filters

  • The European Innovation Network is working to support the European medical innovation ecosystem by facilitating early dialogue between developers of medicines and regulators, as well as providing a platform for regulators to share information, good practices and expertise.

    • Eleonora Agricola
    • Caroline Auriche-Benichou
    • Katarzyna Zywiec
    Comments & Opinion
    Nature Reviews Drug Discovery
    Volume: 23, P: 405-406

  • Launching in 2025, the European Platform for Regulatory Science Research will bring together academia, regulators and other stakeholders to accelerate collaborative regulatory science research solutions.

    • Liese Barbier
    • Pierpaolo Moscariello
    • Anna Maria Gerdina Pasmooij
    Comments & Opinion
    Nature Reviews Drug Discovery
    Volume: 24, P: 485-486

  • A very small number of people with rare diseases caused by unique genetic variants have been treated with therapies developed specifically for them, known as N-of-1 therapies. This Review discusses advances and challenges for N-of-1 therapies based on cases in which they have been successfully developed, highlights why the traditional drug development and reimbursement pathway is not fit for purpose in this field, and provides a roadmap for the development of these individualized therapies.

    • Anneliene H. Jonker
    • Elena-Alexandra Tataru
    • Annemieke Aartsma-Rus
    Reviews
    Nature Reviews Drug Discovery
    Volume: 24, P: 40-56