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Showing 101–150 of 157 results

Advanced filters: Author: Anna T. Webb Clear advanced filters

A massive, dead disk galaxy in the early Universe

When the Universe was just 3 billion years old, half of the most massive galaxies had already ceased star formation, and such a galaxy has now been observed using gravitational lensing, unexpectedly turning out to be a compact, fast-spinning disk galaxy rather than a proto-bulge galaxy.

Sune Toft
Johannes Zabl
Charles L. Steinhardt
Research22 Jun 2017
Nature

Volume: 546, P: 510-513
Comprehensive reanalysis for CNVs in ES data from unsolved rare disease cases results in new diagnoses

German Demidov
Burcu Yaldiz
Steven Laurie
ResearchOpen Access26 Oct 2024
npj Genomic Medicine

Volume: 9, P: 1-24
CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers

Nichola Johnson
Sarah Maguire
Olivia Fletcher
ResearchOpen Access26 Jan 2021
British Journal of Cancer

Volume: 124, P: 842-854
Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2

Douglas Easton and colleagues report results of a large multistage genome-wide association study of breast cancer. The study identifies two new breast cancer risk loci on chromosomes 3p24 and 17q23.2.

Shahana Ahmed
Gilles Thomas
Douglas F Easton
Research29 Mar 2009
Nature Genetics

Volume: 41, P: 585-590
Author Correction: Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

Dami A. Collier
Anna De Marco
Ravindra K. Gupta
Amendments and Corrections21 Jul 2022
Nature

Volume: 608, P: E24
Heterogeneity of late-infantile neuronal ceroid lipofuscinosis

Nanbert Zhong
Dorota N Moroziewicz
W Ted Brown
Research01 Nov 2000
Genetics in Medicine

Volume: 2, P: 312-318
Publisher Correction: Whole-genome sequencing of a sporadic primary immunodeficiency cohort

James E. D. Thaventhiran
Hana Lango Allen
Kenneth G. C. Smith
Amendments and Corrections17 Jul 2020
Nature

Volume: 584, P: E2
Polyploidy can drive rapid adaptation in yeast

In vitro evolution experiments on haploid, diploid, and tetraploid yeast strains show that adaptation is faster in tetraploids, providing direct quantitative evidence that in some environments polyploidy can accelerate evolutionary adaptation.

Anna M. Selmecki
Yosef E. Maruvka
David Pellman
Research02 Mar 2015
Nature

Volume: 519, P: 349-352
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

Miles Parkes and colleagues report results of a large genome-wide association meta-analysis and replication study for Crohn's disease. They identify 30 new susceptibility loci for this inflammatory bowel disease and implicate several interesting candidate genes in disease pathogenesis.

Andre Franke
Dermot P B McGovern
Miles Parkes
Research21 Nov 2010
Nature Genetics

Volume: 42, P: 1118-1125
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

John Rioux and colleagues report results of a large genome-wide association meta-analysis and follow-up study of ulcerative colitis. They identify 29 new risk loci for this inflammatory disease and show that many risk loci are shared between ulcerative colitis and Crohn's disease.

Carl A Anderson
Gabrielle Boucher
John D Rioux
Research06 Feb 2011
Nature Genetics

Volume: 43, P: 246-252
Generating and validating renewable affimer protein binding reagents targeting SH2 domains

Sophie J. Heseltine
Gregory J. Billenness
Darren C. Tomlinson
ResearchOpen Access16 Nov 2024
Scientific Reports

Volume: 14, P: 1-14
Absence of PD-L1 on tumor cells is associated with reduced MHC I expression and PD-L1 expression increases in recurrent serous ovarian cancer

Stefanie Aust
Sophie Felix
Dietmar Pils
ResearchOpen Access07 Mar 2017
Scientific Reports

Volume: 7, P: 1-12
Author Correction: SARS-CoV-2 evolution during treatment of chronic infection

Steven A. Kemp
Dami A. Collier
Ravindra K. Gupta
Amendments and Corrections21 Jul 2022
Nature

Volume: 608, P: E23
Author Correction: A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers

Juliette Coignard
Michael Lush
Antonis C. Antoniou
Amendments and CorrectionsOpen Access14 May 2021
Nature Communications

Volume: 12, P: 1-2
Exome sequencing identifies HELB as a novel susceptibility gene for non-mucinous, non-high-grade-serous epithelial ovarian cancer

Ed M. Dicks
Jonthan P. Tyrer
Paul D. P. Pharoah
ResearchOpen Access12 Feb 2025
European Journal of Human Genetics

Volume: 33, P: 297-303
A comprehensive iterative approach is highly effective in diagnosing individuals who are exome negative

Vandana Shashi
Kelly Schoch
Allison Zheng
Research15 Jun 2018
Genetics in Medicine

Volume: 21, P: 161-172
Pre-diagnosis tea and coffee consumption and survival after a diagnosis of ovarian cancer: results from the Ovarian Cancer Association Consortium

Christina M. Nagle
Torukiri I. Ibiebele
Penelope M. Webb
ResearchOpen Access18 Jul 2024
British Journal of Cancer

Volume: 131, P: 1043-1049
Damaged microtubules can inactivate BCL-2 by means of the mTOR kinase

Angela Calastretti
Anna Bevilacqua
Angelo Nicolin
Research12 Oct 2001
Oncogene

Volume: 20, P: 6172-6180
Publisher Correction: Genomic reconstruction of the SARS CoV-2 epidemic in England

Harald S. Vöhringer
Theo Sanderson
Moritz Gerstung
Amendments and CorrectionsOpen Access07 Jun 2022
Nature

Volume: 606, P: E18
A polygenic resilience score moderates the genetic risk for schizophrenia

Jonathan L. Hess
Daniel S. Tylee
Stephen J. Glatt
ResearchOpen Access06 Sept 2019
Molecular Psychiatry

Volume: 26, P: 800-815
Refined cut-off for TP53 immunohistochemistry improves prediction of TP53 mutation status in ovarian mucinous tumors: implications for outcome analyses

Eun Young Kang
Dane Cheasley
Kylie L. Gorringe
Research28 Jul 2020
Modern Pathology

Volume: 34, P: 194-206
At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods

Munib Mesinovic
Xin Ci Wong
David Zucman
ResearchOpen Access16 Jul 2024
Scientific Reports

Volume: 14, P: 1-43
Genome-wide association analyses of ovarian cancer patients undergoing primary debulking surgery identify candidate genes for residual disease

Dhanya Ramachandran
Jonathan P. Tyrer
Florian Heitz
ResearchOpen Access05 Mar 2024
npj Genomic Medicine

Volume: 9, P: 1-12
No time to rest: seasonal dynamics of non-structural carbohydrates in twigs of three Mediterranean tree species suggest year-round activity

Anna M. Davidson
Sylvia T. Le
M. A. Zwieniecki
ResearchOpen Access04 Mar 2021
Scientific Reports

Volume: 11, P: 1-12
Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk

Richard Houlston and colleagues report a genome-wide association study for colorectal cancer. They report three loci newly associated with colorectal cancer, bringing the total number of common susceptibility loci to 20.

Malcolm G Dunlop
Sara E Dobbins
Richard S Houlston
Research27 May 2012
Nature Genetics

Volume: 44, P: 770-776
Paclitaxel sensitivity in relation to ABCB1 expression, efflux and single nucleotide polymorphisms in ovarian cancer

Bo Gao
Amanda Russell
Anna deFazio
ResearchOpen Access09 May 2014
Scientific Reports

Volume: 4, P: 1-9
Identification of rare-disease genes using blood transcriptome sequencing and large control cohorts

A diagnostic tool based on blood RNA-seq is shown to identify causal genes and variants linked to clinical phenotypes in individuals with rare diseases for which whole-exome genetic sequencing was uninformative.

Laure Frésard
Craig Smail
Stephen B. Montgomery
Research03 Jun 2019
Nature Medicine

Volume: 25, P: 911-919
Reward-related predictors of symptom change in behavioral activation therapy for anhedonic adolescents: a multimodal approach

Christian A. Webb
Laura Murray
Diego A. Pizzagalli
Research28 Oct 2022
Neuropsychopharmacology

Volume: 48, P: 623-632
A resource of lipidomics and metabolomics data from individuals with undiagnosed diseases

Jennifer E. Kyle
Kelly G. Stratton
Thomas O. Metz
ResearchOpen Access21 Apr 2021
Scientific Data

Volume: 8, P: 1-12
Use of common analgesic medications and ovarian cancer survival: results from a pooled analysis in the Ovarian Cancer Association Consortium

Suzanne C Dixon
Christina M Nagle
Penelope M Webb
ResearchOpen Access28 Mar 2017
British Journal of Cancer

Volume: 116, P: 1223-1228
Treatment effect heterogeneity following type 2 diabetes treatment with GLP1-receptor agonists and SGLT2-inhibitors: a systematic review

Young, McInnes, Massey et al. systematically review published studies evaluating features associated with heterogenous treatment effects for SGLT2-inhibitor and GLP1-receptor agonist therapies in people with type 2 diabetes. They find limited current evidence on treatment effect heterogeneity, for glycaemic, cardiovascular and renal outcomes.

Katherine G. Young
Eram Haider McInnes
Paul W. Franks
ResearchOpen Access05 Oct 2023
Communications Medicine

Volume: 3, P: 1-20
Correction: Polygenic risk modeling for prediction of epithelial ovarian cancer risk

Eileen O. Dareng
Jonathan P. Tyrer
Paul D. P. Pharoah
Amendments and CorrectionsOpen Access22 Mar 2022
European Journal of Human Genetics

Volume: 30, P: 630-631
Looking beyond the exome: a phenotype-first approach to molecular diagnostic resolution in rare and undiagnosed diseases

Loren D M Pena
Yong-Hui Jiang
Vandana Shashi
Research14 Sept 2017
Genetics in Medicine

Volume: 20, P: 464-469
Neural responsivity to social rewards in autistic female youth

Katherine E. Lawrence
Leanna M. Hernandez
Julie Wolf
ResearchOpen Access02 Jun 2020
Translational Psychiatry

Volume: 10, P: 1-12
Generation of a Jurkat-based fluorescent reporter cell line to evaluate lipid antigen interaction with the human iNKT cell receptor

Piotr Humeniuk
Sabine Geiselhart
Karin Hoffmann-Sommergruber
ResearchOpen Access15 May 2019
Scientific Reports

Volume: 9, P: 1-12
Consequent and intensified relapse therapy improved survival in pediatric AML: results of relapse treatment in 379 patients of three consecutive AML-BFM trials

A Sander
M Zimmermann
U Creutzig
Research10 Jun 2010
Leukemia

Volume: 24, P: 1422-1428
Publisher Correction: Gene expression imputation across multiple brain regions provides insights into schizophrenia risk

Laura M. Huckins
Amanda Dobbyn
Eli A. Stahl
Amendments and Corrections13 May 2019
Nature Genetics

Volume: 51, P: 1068
History of thyroid disease and survival of ovarian cancer patients: results from the Ovarian Cancer Association Consortium, a brief report

Albina N Minlikeeva
Jo L Freudenheim
Kirsten B Moysich
ResearchOpen Access17 Aug 2017
British Journal of Cancer

Volume: 117, P: 1063-1069
Hormone Treatment Gives No Benefit Against Cognitive Changes Caused by Acute Sleep Deprivation in Postmenopausal Women

Maija Karakorpi
Paula Alhola
Päivi Polo-Kantola
Research15 Mar 2006
Neuropsychopharmacology

Volume: 31, P: 2079-2088
Small-scale mutations are infrequent as mechanisms of resistance in post-PARP inhibitor tumour samples in high grade serous ovarian cancer

Nikki L. Burdett
Madelynne O. Willis
Elizabeth L. Christie
ResearchOpen Access11 Dec 2023
Scientific Reports

Volume: 13, P: 1-10
Adult height is associated with increased risk of ovarian cancer: a Mendelian randomisation study

Suzanne C. Dixon-Suen
Christina M. Nagle
Penelope M. Webb
ResearchOpen Access20 Mar 2018
British Journal of Cancer

Volume: 118, P: 1123-1129
Microbial Community Dynamics During Lake Ice Freezing

Timothy M. Butler
Anna-Catharina Wilhelm
Stephen M. Techtmann
ResearchOpen Access17 Apr 2019
Scientific Reports

Volume: 9, P: 1-11
Modulation of EEG theta by naturalistic social content is not altered in infants with family history of autism

Rianne Haartsen
Tony Charman
Agnes Volein
ResearchOpen Access01 Dec 2022
Scientific Reports

Volume: 12, P: 1-14
Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

Till F. M. Andlauer
Jose Guzman-Parra
Marcella Rietschel
ResearchOpen Access11 Nov 2019
Molecular Psychiatry

Volume: 26, P: 1286-1298
SF3B1 mutations induce R-loop accumulation and DNA damage in MDS and leukemia cells with therapeutic implications

Shalini Singh
Doaa Ahmed
Jacqueline Boultwood
ResearchOpen Access19 Feb 2020
Leukemia

Volume: 34, P: 2525-2530
Impact of cytogenetics on the prognosis of adults with de novo AML in first relapse

A Weltermann
C Fonatsch
K Lechner
Research11 Dec 2003
Leukemia

Volume: 18, P: 293-302
Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder

Simone de Jong et al. examine the balance of common and rare risk for psychiatric disorders in a large family with high incidence of Bipolar Disorder and Major Depressive Disorder. They find that increased polygenic risk over generations could be partially due to assortative mating, which may explain the observation of anticipation in mood disorders.

Simone de Jong
Mateus Jose Abdalla Diniz
Gerome Breen
ResearchOpen Access08 Oct 2018
Communications Biology

Volume: 1, P: 1-10
Age at first birth in women is genetically associated with increased risk of schizophrenia

Guiyan Ni
Jacob Gratten
Michael C. O’Donovan
ResearchOpen Access05 Jul 2018
Scientific Reports

Volume: 8, P: 1-14
Recreational physical inactivity and mortality in women with invasive epithelial ovarian cancer: evidence from the Ovarian Cancer Association Consortium

Rikki A Cannioto
Michael J LaMonte
Kirsten B Moysich
ResearchOpen Access14 Jun 2016
British Journal of Cancer

Volume: 115, P: 95-101
Hair Cortisol in Twins: Heritability and Genetic Overlap with Psychological Variables and Stress-System Genes

Liz Rietschel
Fabian Streit
Marcella Rietschel
ResearchOpen Access10 Nov 2017
Scientific Reports

Volume: 7, P: 1-15

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