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Anemia prevalence in women of reproductive age in low- and middle-income countries between 2000 and 2018

Geospatial estimates of the prevalence of anemia in women of reproductive age across 82 low-income and middle-income countries reveals considerable heterogeneity and inequality at national and subnational levels, with few countries on track to meet the WHO Global Nutrition Targets by 2030.

Damaris Kinyoki
Aaron E. Osgood-Zimmerman
Simon I. Hay
ResearchOpen Access12 Oct 2021
Nature Medicine

Volume: 27, P: 1761-1782
Plasmacytoid dendritic cells control homeostasis of megakaryopoiesis

Plasmacytoid dendritic cells monitor the bone marrow for apoptotic megakaryocytes (MKs) and deliver IFNα to the MK niche, triggering local on-demand proliferation and maturation of MK progenitors.

Florian Gaertner
Hellen Ishikawa-Ankerhold
Steffen Massberg
ResearchOpen Access10 Jul 2024
Nature

Volume: 631, P: 645-653
Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017

Fine-scale geospatial mapping of overweight and wasting (two components of the double burden of malnutrition) in 105 LMICs shows that overweight has increased from 5.2% in 2000 to 6.0% in children under 5 in 2017. Although overall wasting decreased over the same period, most countries are not on track to meet the World Health Organization’s Global Nutrition Target of <5% in over half of LMICs by 2025.

Damaris K. Kinyoki
Jennifer M. Ross
Simon I. Hay
ResearchOpen Access20 Apr 2020
Nature Medicine

Volume: 26, P: 750-759
Ontogeny of arterial macrophages defines their functions in homeostasis and inflammation

Arterial macrophages develop from either yolk sac or bone marrow progenitors. Here, the author show that ageing-induced reduction of arterial macrophages is not replenished by bone marrow-derived cells, but under inflammatory conditions circulating monocytes are recruited to maintain homeostasis, while arterial macrophages of yolk sac origin carry out tissue repair.

Tobias Weinberger
Dena Esfandyari
Christian Schulz
ResearchOpen Access11 Sept 2020
Nature Communications

Volume: 11, P: 1-16
Cathelicidins prime platelets to mediate arterial thrombosis and tissue inflammation

Cathelicidins are antimicrobial peptides that eliminate pathogens and contribute to the innate immune response. Here the authors show that neutrophil-derived LL-37/CRAMP induces platelet activation and promotes arterial thrombosis and thrombo-inflammation.

Joachim Pircher
Thomas Czermak
Christian Schulz
ResearchOpen Access18 Apr 2018
Nature Communications

Volume: 9, P: 1-15
Author Correction: Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017

Damaris K. Kinyoki
Jennifer M. Ross
Simon I. Hay
Amendments and CorrectionsOpen Access02 Jul 2020
Nature Medicine

Volume: 26, P: 1308

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Anemia prevalence in women of reproductive age in low- and middle-income countries between 2000 and 2018

Plasmacytoid dendritic cells control homeostasis of megakaryopoiesis

Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017

Ontogeny of arterial macrophages defines their functions in homeostasis and inflammation

Cathelicidins prime platelets to mediate arterial thrombosis and tissue inflammation

Author Correction: Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017

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