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Advanced filters: Author: Annabelle Rajalu Clear advanced filters

  • This study identifies an altered chromatin conformation associated to a cardiac disorder observed in 7 independent families. A deletion of 2 diverging CTCF binding sites on 4q25 induces TAD fusion and leads to PITX2 expression dysregulation.

    • Manon Baudic
    • Hiroshige Murata
    • Julien Barc
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-15