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Showing 1–13 of 13 results
Advanced filters: Author: Anne Condon Clear advanced filters

  • A high-resolution astrochronological framework for the early Ediacaran refines the timing of key events, linking glaciation, carbon isotope excursions, and fossil assemblages to gradual ecosystem complexity and rapid biogeochemical transitions.

    • Tan Zhang
    • Chao Ma
    • Mingcai Hou
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-14

  • Puzzarini and colleagues explore the computational characterization of medium-sized molecular systems using different spectroscopic techniques. The Primer provides essential information about the characteristics, accuracy and limitations of current computational approaches used for modelling spectroscopic phenomena with a focus on estimating error bars, limitations and coupling interpretability to accuracy.

    • Vincenzo Barone
    • Silvia Alessandrini
    • Cristina Puzzarini
    Reviews
    Nature Reviews Methods Primers
    Volume: 1, P: 1-27

  • The idea that artificial neural networks could be based on molecular components is not new, but making such a system has been difficult. A network of four artificial neurons made from DNA has now been created. See Letter p.368

    • Anne Condon
    News & Views
    Nature
    Volume: 475, P: 304-305

  • The transplantation of residues from a selective to a nonselective haloalkane dehalogenase yields the correct active site geometry but not function. Computational and biophysical results explain this disparity, showing that the dynamics and hydration of the engineered protein match its parent, not its target.

    • Jan Sykora
    • Jan Brezovsky
    • Jiri Damborsky
    Research
    Nature Chemical Biology
    Volume: 10, P: 428-430

  • The sequence, structure and folding properties of DNA are being exploited in innovative ways, thereby expanding the uses of DNA beyond its natural calling. This article examines those applications, which range from disease diagnostics to molecular computing.

    • Anne Condon
    Reviews
    Nature Reviews Genetics
    Volume: 7, P: 565-575

  • Bacterial RNA degradation is typically initiated by endoribonucleases and followed by exoribonucleases. Here the authors report the targetome of endoRNase Y in Streptococcus pyogenes, revealing the interplay between RNase Y and 3′-to-5′ exoribonuclease PNPase and YhaM.

    • Laura Broglia
    • Anne-Laure Lécrivain
    • Emmanuelle Charpentier
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-12

  • Assessing functional impact of mutations in cancer on gene expression can improve our understanding of cancer biology and may identify potential therapeutic targets. Here, Ding et al. describe a novel statistical model named xseq for a systematic survey of how mutations impact transcriptome landscapes across 12 different tumour types.

    • Jiarui Ding
    • Melissa K. McConechy
    • Sohrab P. Shah
    ResearchOpen Access
    Nature Communications
    Volume: 6, P: 1-13

  • Information-carrying DNA strands can be used to perform simple computations, but have so far been little more than toys. Can molecular computers be more broadly useful — in medicine, for instance?

    • Anne Condon
    News & Views
    Nature
    Volume: 429, P: 351-352