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Advanced filters: Author: Anne Grotevendt Clear advanced filters
  • Anna Köttgen and colleagues report genome-wide association studies for serum urate in over 140,000 individuals from the Global Urate Genetics Consortium (GUGC). They identify 18 loci newly associated with serum urate concentrations and confirm 10 known loci, characterize their associations with gout and include a network analysis suggesting a role for inhibins-activins pathways in regulating urate homeostasis.

    • Anna Köttgen
    • Eva Albrecht
    • Christian Gieger
    Research
    Nature Genetics
    Volume: 45, P: 145-154