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Airway environment drives the selection of quorum sensing mutants and promote Staphylococcus aureus chronic lifestyle

This study by Ding et al reveals that the quorum-sensing dysfunction typically encountered in lung-adapted Staphylococcus aureus isolates could be selected by an enhanced ability to consume sialic acid released from airway mucins by the microbiota.

Xiongqi Ding
Catherine Robbe-Masselot
Anne Jamet
ResearchOpen Access08 Dec 2023
Nature Communications

Volume: 14, P: 1-13
A sequence of mitochondrial DNA is associated with the onset of senescence in a fungus

Corinne Vierny
Anne-Marie Keller
Léon Belcour
Research13 May 1982
Nature

Volume: 297, P: 157-159
Targeting Type IV pili as an antivirulence strategy against invasive meningococcal disease

Phenothiazines inhibit Type IV pili function in Neisseria meningitidis and protect against bacterial colonization of blood vessels and lethality during infection.

Kevin Denis
Marion Le Bris
Sandrine Bourdoulous
Research25 Mar 2019
Nature Microbiology

Volume: 4, P: 972-984
Cytoplasmic FUS triggers early behavioral alterations linked to cortical neuronal hyperactivity and inhibitory synaptic defects

Mutations in the RNA binding protein FUS are associated with ALS. Here the authors show that in FUS knock-in mice there is a progressive increase in neuronal activity in the frontal cortex which is associated with altered synaptic gene expression.

Jelena Scekic-Zahirovic
Inmaculada Sanjuan-Ruiz
Luc Dupuis
ResearchOpen Access21 May 2021
Nature Communications

Volume: 12, P: 1-19
Transcriptional outcome of telomere signalling

The role of telomeric factors as guardians of chromosome ends from threats to genome integrity (such as degradation and inappropriate DNA damage response activation) has long been appreciated. This Review discusses the extratelomeric activity of these factors and how they can regulate the transcription of genes involved in metabolism, immunity and differentiation.

Jing Ye
Valérie M. Renault
Eric Gilson
Reviews10 Jun 2014
Nature Reviews Genetics

Volume: 15, P: 491-503
Dual proteomics of infected macrophages reveal bacterial and host players involved in the Francisella intracellular life cycle and cell to cell dissemination by merocytophagy

Héloïse Rytter
Kevin Roger
Alain Charbit
ResearchOpen Access02 Apr 2024
Scientific Reports

Volume: 14, P: 1-13
HadD, a novel fatty acid synthase type II protein, is essential for alpha- and epoxy-mycolic acid biosynthesis and mycobacterial fitness

Cyril Lefebvre
Richard Boulon
Annaïk Quémard
ResearchOpen Access16 Apr 2018
Scientific Reports

Volume: 8, P: 1-15

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Airway environment drives the selection of quorum sensing mutants and promote Staphylococcus aureus chronic lifestyle

A sequence of mitochondrial DNA is associated with the onset of senescence in a fungus

Targeting Type IV pili as an antivirulence strategy against invasive meningococcal disease

Cytoplasmic FUS triggers early behavioral alterations linked to cortical neuronal hyperactivity and inhibitory synaptic defects

Transcriptional outcome of telomere signalling

Dual proteomics of infected macrophages reveal bacterial and host players involved in the Francisella intracellular life cycle and cell to cell dissemination by merocytophagy

HadD, a novel fatty acid synthase type II protein, is essential for alpha- and epoxy-mycolic acid biosynthesis and mycobacterial fitness

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Airway environment drives the selection of quorum sensing mutants and promote Staphylococcus aureus chronic lifestyle

A sequence of mitochondrial DNA is associated with the onset of senescence in a fungus

Targeting Type IV pili as an antivirulence strategy against invasive meningococcal disease

Cytoplasmic FUS triggers early behavioral alterations linked to cortical neuronal hyperactivity and inhibitory synaptic defects

Transcriptional outcome of telomere signalling

Dual proteomics of infected macrophages reveal bacterial and host players involved in the Francisella intracellular life cycle and cell to cell dissemination by merocytophagy

HadD, a novel fatty acid synthase type II protein, is essential for alpha- and epoxy-mycolic acid biosynthesis and mycobacterial fitness

Search

Quick links