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Showing 1–4 of 4 results
Advanced filters: Author: Anne L'Hernault Clear advanced filters

  • Measurements of subclonal expansion of ctDNA in the plasma before surgery may enable the prediction of future metastatic subclones, offering the possibility for early intervention in patients with non-small-cell lung cancer.

    • Christopher Abbosh
    • Alexander M. Frankell
    • Charles Swanton
    Research
    Nature
    Volume: 616, P: 553-562

  • Here, using computational integration of multi-omics data, the authors provide a detailed transcriptome and translatome of herpes simplex virus 1 (HSV-1), including previously unidentified ORFs and N-terminal extensions. The study also provides a HSV-1 genome browser and should be a valuable resource for further research.

    • Adam W. Whisnant
    • Christopher S. Jürges
    • Lars Dölken
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-14

  • Herpes simplex virus 1 (HSV-1) efficiently shuts down host gene expression in infected cells. Here Rutkowski et al. analyse the genome-wide changes in transcription and translation in infected cells, and show that HSV-1 triggers an extensive disruption of transcription termination of cellular genes.

    • Andrzej J. Rutkowski
    • Florian Erhard
    • Lars Dölken
    ResearchOpen Access
    Nature Communications
    Volume: 6, P: 1-15