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Showing 1–7 of 7 results
Advanced filters: Author: Anne Venner Clear advanced filters

  • Cell groups in the hypothalamic suprachiasmatic clock contribute to the genesis of circadian rhythms. The authors identified two populations of vasoactive intestinal polypeptide-expressing neurons in the suprachiasmatic nucleus which regulate locomotor circadian rhythm in mice.

    • William D. Todd
    • Anne Venner
    • Patrick M. Fuller
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-20

  • Todd et al. show a daily rhythm in aggression propensity in male mice and reveal a novel polysynaptic circuit within the hypothalamus by which the central circadian clock (the suprachiasmatic nucleus) influences neurons that regulate attack behavior.

    • William D. Todd
    • Henning Fenselau
    • Clifford B. Saper
    Research
    Nature Neuroscience
    Volume: 21, P: 717-724

  • Sleep and wakefulness is stabilized by a population of orexin-expressing neurons. In this study, the authors demonstrate how these neurons drive arousal by silencing sleep-promoting neurons in the ventrolateral preoptic nucleus.

    • Roberto De Luca
    • Stefano Nardone
    • Elda Arrigoni
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-15

  • Dorsal raphe 5HT(DRSert) neurons regulate arousal from hypercapnia by their projections to the neurons in the external lateral parabrachial nucleus (PBel) that are glutamatergic and also express calcitonin gene related peptide (PBelCGRP). The DRSert input to the PBel modulates the arousal system to rising levels of blood CO2, and may be mediated by 5HT2a receptors on the PBelCGRP neurons.

    • Satvinder Kaur
    • Roberto De Luca
    • Clifford B. Saper
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-15

  • The mammalian basal forebrain controls cortical rhythm and wake-sleep. Anaclet et al.use genetically-targeted chemogenetic systems to activate or inhibit cholinergic, glutamatergic or GABAergic neurons in this region, and reveal their contributions to behavioral and electrocortical arousal in behaving mice.

    • Christelle Anaclet
    • Nigel P. Pedersen
    • Patrick M. Fuller
    ResearchOpen Access
    Nature Communications
    Volume: 6, P: 1-14

  • Supramammillary nucleus (SuM) neurons have been studied in the context of REM sleep but their possible role in mediating wakefulness is not known. Here the authors elucidate the distinct functional contributions of three subpopulations in the SuM on electrographical and behavioral arousal in mice using genetically targeted approaches.

    • Nigel P. Pedersen
    • Loris Ferrari
    • Patrick M. Fuller
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-16