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Showing 51–86 of 86 results

Advanced filters: Author: Annette Fox Clear advanced filters

Chemical inhibition of N-WASP by stabilization of a native autoinhibited conformation

Jeffrey R Peterson
Lincoln C Bickford
Michael K Rosen
Research04 Jul 2004
Nature Structural & Molecular Biology

Volume: 11, P: 747-755
MHC class II proteins mediate cross-species entry of bat influenza viruses

The DR isotype of the human leukocyte antigen of the MHC class II—or its homologues in bats, pigs, mice and chickens—is an essential cell entry determinant for bat influenza A viruses.

Umut Karakus
Thiprampai Thamamongood
Silke Stertz
Research20 Feb 2019
Nature

Volume: 567, P: 109-112
Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept

The authors defined a roadmap for investigating the genetic covariance between structural or functional brain phenotypes and risk for psychiatric disorders. Their proof-of-concept study using the largest available common variant data sets for schizophrenia and volumes of several (mainly subcortical) brain structures did not find evidence of genetic overlap.

Barbara Franke
Jason L Stein
Patrick F Sullivan
Research01 Feb 2016
Nature Neuroscience

Volume: 19, P: 420-431
Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

Josée Dupuis
Claudia Langenberg
Inês Barroso
Amendments and Corrections01 May 2010
Nature Genetics

Volume: 42, P: 464
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

Eli Stahl and colleagues report results of a genome-wide association study meta-analysis and replication study for rheumatoid arthritis. Their work identifies several new risk loci and highlights genetic overlap with other autoimmune diseases.

Eli A Stahl
Soumya Raychaudhuri
Robert M Plenge
Research09 May 2010
Nature Genetics

Volume: 42, P: 508-514
Author Correction: Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Brian W. Kunkle
Benjamin Grenier-Boley
Margaret A. Pericak-Vance
Amendments and Corrections15 Aug 2019
Nature Genetics

Volume: 51, P: 1423-1424
Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk

Soumya Raychaudhuri and colleagues demonstrate the utility of GRAIL, a software program used to prioritize results from genome-wide association studies for further replication, applied here to rheumatoid arthritis. The authors seek replication of their predictions in additional independent cohorts and report three new genetic loci associated with RA susceptibility.

Soumya Raychaudhuri
Brian P Thomson
Robert M Plenge
Research08 Nov 2009
Nature Genetics

Volume: 41, P: 1313-1318
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

Mark McCarthy, Michael Boehnke, Andrew Morris and colleagues perform large-scale association analyses using the Metabochip to gain insights into the genetic architecture of type 2 diabetes. They report several new susceptibility loci, including two that show sex-differentiated effects on disease risk.

Andrew P Morris
Benjamin F Voight
Mark I McCarthy
Research12 Aug 2012
Nature Genetics

Volume: 44, P: 981-990
Author Correction: Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses

Benedict D. Michael
Cordelia Dunai
David K. Menon
Amendments and CorrectionsOpen Access04 Apr 2024
Nature Communications

Volume: 15, P: 1
FTO genotype is associated with phenotypic variability of body mass index

A meta-analysis of genome-wide association studies of phenotypic variation for height and body mass index in human populations using 170,000 samples shows that one single nucleotide polymorphism at the FTO locus, which is associated with obesity, is also associated with phenotypic variation.

Jian Yang
Ruth J. F. Loos
Peter M. Visscher
Research16 Sept 2012
Nature

Volume: 490, P: 267-272
Risk willingness in multiple system atrophy and Parkinson’s disease understanding patient preferences

Alexander Maximilian Bernhardt
Marc Oeller
Wolfgang Hermann Oertel
ResearchOpen Access15 Aug 2024
npj Parkinson's Disease

Volume: 10, P: 1-10
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

Julie Williams, Michael Owen and colleagues report staged follow-up and meta-analyses of genome-wide association studies for Alzheimer's disease from the GERAD+ consortium. They identify common variants at ABCA7 and MS4A6A/MS4A4E associated with Alzheimer's disease and support for several additional susceptibility loci.

Paul Hollingworth
Denise Harold
Julie Williams
Research03 Apr 2011
Nature Genetics

Volume: 43, P: 429-435
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

Philippe Amouyel, Julie Williams, Gerard Schellenberg, Sudha Seshadri and colleagues report a meta-analysis of genome-wide association studies for late-onset Alzheimer's disease in 17,008 cases and 37,154 controls with replication in an additional 8,572 cases and 11,312 controls. They identify 11 loci newly associated with Alzheimer's disease.

Jean-Charles Lambert
Carla A Ibrahim-Verbaas
Philippe Amouyel
Research27 Oct 2013
Nature Genetics

Volume: 45, P: 1452-1458
Publisher Correction: Understanding the genetic complexity of puberty timing across the allele frequency spectrum

Katherine A. Kentistou
Lena R. Kaisinger
Ken K. Ong
Amendments and CorrectionsOpen Access09 Jul 2024
Nature Genetics

Volume: 56, P: 1763-1764
Antibody responses against influenza A decline with successive years of annual influenza vaccination

Sheena G. Sullivan
Arseniy Khvorov
Annette Fox
ResearchOpen Access17 Jan 2025
npj Vaccines

Volume: 10, P: 1-10
Genetic evidence of assortative mating in humans

Using whole-genome data for single-nucleotide polymorphism and results from genome-wide association studies, the authors show that people’s preference for pairing with those with similar phenotypic traits has genetic causes and consequences.

Matthew R. Robinson
Aaron Kleinman
Peter M. Visscher
Research09 Jan 2017
Nature Human Behaviour

Volume: 1, P: 1-13
Derivation, external and clinical validation of a deep learning approach for detecting intracranial hypertension

Faris Gulamali
Pushkala Jayaraman
Girish N. Nadkarni
ResearchOpen Access05 Sept 2024
npj Digital Medicine

Volume: 7, P: 1-7
Germline variants at SOHLH2 influence multiple myeloma risk

Laura Duran-Lozano
Gudmar Thorleifsson
Björn Nilsson
ResearchOpen Access19 Apr 2021
Blood Cancer Journal

Volume: 11, P: 1-8
Author Correction: Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores

Itziar de Rojas
Sonia Moreno-Grau
Agustín Ruiz
Amendments and CorrectionsOpen Access09 Feb 2023
Nature Communications

Volume: 14, P: 1-2
Comparative DNA Methylation Profiling Reveals an Immunoepigenetic Signature of HIV-related Cognitive Impairment

Michael J. Corley
Christian Dye
Alika K. Maunakea
ResearchOpen Access15 Sept 2016
Scientific Reports

Volume: 6, P: 1-13
Parkinson’s families project: a UK-wide study of early onset and familial Parkinson’s disease

Clodagh Towns
Zih-Hua Fang
Raquel Real
ResearchOpen Access17 Oct 2024
npj Parkinson's Disease

Volume: 10, P: 1-13
Uhthoff's phenomena in MS—clinical features and pathophysiology

Uhthoff's phenomena are transient disturbances in neurological functioning that can be triggered by an increase in core body temperature in patients with multiple sclerosis (MS). In this article, Frohman et al. discuss the pathophysiological underpinnings of Uhthoff's phenomena, and highlight the importance of differentiating between these events and true MS exacerbations in the clinic.

Teresa C. Frohman
Scott L. Davis
Elliot M. Frohman
Reviews04 Jun 2013
Nature Reviews Neurology

Volume: 9, P: 535-540
Publisher Correction: Whole-genome sequencing of a sporadic primary immunodeficiency cohort

James E. D. Thaventhiran
Hana Lango Allen
Kenneth G. C. Smith
Amendments and Corrections17 Jul 2020
Nature

Volume: 584, P: E2
First observation of radiolytic bubble formation in unstirred nano-powder sludges and a consistent model thereof

Mel O’Leary
Aliaksandr Baidak
Fred Currell
ResearchOpen Access24 Nov 2021
Scientific Reports

Volume: 11, P: 1-12
Comparative survival analysis of multiparametric tests—when molecular tests disagree—A TEAM Pathology study

John M. S. Bartlett
Jane Bayani
Daniel Rea
ResearchOpen Access08 Jul 2021
npj Breast Cancer

Volume: 7, P: 1-13
Multi-ancestry genome-wide gene–sleep interactions identify novel loci for blood pressure

Heming Wang
Raymond Noordam
Diana van Heemst
Research15 Apr 2021
Molecular Psychiatry

Volume: 26, P: 6293-6304
Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci

Lisa de las Fuentes
Yun Ju Sung
Myriam Fornage
Research05 May 2020
Molecular Psychiatry

Volume: 26, P: 2111-2125
Observation of dose-rate dependence in a Fricke dosimeter irradiated at low dose rates with monoenergetic X-rays

Mel O’Leary
Daria Boscolo
Fred J. Currell
ResearchOpen Access16 Mar 2018
Scientific Reports

Volume: 8, P: 1-9
TERT promoter mutation in adult granulosa cell tumor of the ovary

Jessica A. Pilsworth
Dawn R. Cochrane
David G. Huntsman
Research15 Feb 2018
Modern Pathology

Volume: 31, P: 1107-1115
Molecular stratification of early breast cancer identifies drug targets to drive stratified medicine

Jane Bayani
Cindy Q. Yao
John M. S. Bartlett
ResearchOpen Access15 Feb 2017
npj Breast Cancer

Volume: 3, P: 1-10
Mobilise-D insights to estimate real-world walking speed in multiple conditions with a wearable device

Cameron Kirk
Arne Küderle
Linda Van Gelder
ResearchOpen Access19 Jan 2024
Scientific Reports

Volume: 14, P: 1-23
Cognitive Characterization of Schizophrenia Risk Variants Involved in Synaptic Transmission: Evidence of CACNA1C's Role in Working Memory

Donna Cosgrove
Omar Mothersill
Gary Donohoe
Research13 Jun 2017
Neuropsychopharmacology

Volume: 42, P: 2612-2622
Anthropometry, DXA, and leptin reflect subcutaneous but not visceral abdominal adipose tissue on MRI in 197 healthy adolescents

Jeanette Tinggaard
Casper P Hagen
Katharina M Main
Research19 Jul 2017
Pediatric Research

Volume: 82, P: 620-628
Correction: TERT promoter mutation in adult granulosa cell tumor of the ovary

Jessica A. Pilsworth
Dawn R. Cochrane
David G. Huntsman
Amendments and Corrections03 Jul 2018
Modern Pathology

Volume: 32, P: 593
Author Correction: Mobilise-D insights to estimate real-world walking speed in multiple conditions with a wearable device

Cameron Kirk
Arne Küderle
Linda Van Gelder
Amendments and CorrectionsOpen Access21 Nov 2024
Scientific Reports

Volume: 14, P: 1-3
Venous thromboembolism laboratory testing (factor V Leiden and factor II c.*97G>A), 2018 update: a technical standard of the American College of Medical Genetics and Genomics (ACMG)

Shulin Zhang
Annette K. Taylor
C. Sue Richards
Reviews05 Oct 2018
Genetics in Medicine

Volume: 20, P: 1489-1498

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