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Advanced filters: Author: Annie Herrig Clear advanced filters

  • Rad23 accompanies ubiquitinated substrates to the proteasome for destruction but manages to avoid degradation. In this study, Fishbainet al.show that Rad23 escapes because it lacks an effective initiation region; therefore, the proteasome is unable to engage the protein and unfold it.

    • Susan Fishbain
    • Sumit Prakash
    • Andreas Matouschek
    Research
    Nature Communications
    Volume: 2, P: 1-9