Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–3 of 3 results
Advanced filters: Author: Anoria K. Haick Clear advanced filters

  • The main challenge for anti-HSV therapy is to target latent virus in ganglionic neurons. Here, the authors report a well-tolerated anti-HSV gene editing approach against HSV which targets latent HSV genomes and leads to reductions of ganglionic viral loads, and viral shedding upon reactivation in mouse models.

    • Martine Aubert
    • Anoria K. Haick
    • Keith R. Jerome
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-14

  • Gene drives are genetic modifications designed to propagate efficiently through a population. Here, the authors develop a viral gene drive against herpes simplex virus 1 (HSV-1) and show that it propagates efficiently during HSV-1 infection in mice.

    • Marius Walter
    • Anoria K. Haick
    • Eric Verdin
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-18

  • Herpes simplex virus establishes lifelong latency in ganglionic neurons, which are the source for recurrent infection. Here Aubert et al. report a promising antiviral therapy based on gene editing with adeno-associated virus-delivered meganucleases, which leads to a significant reduction in ganglionic HSV loads and HSV reactivation.

    • Martine Aubert
    • Daniel E. Strongin
    • Keith R. Jerome
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-15