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Showing 1–5 of 5 results
Advanced filters: Author: Anthony Fullam Clear advanced filters

  • Here, the authors built a non-redundant catalogue of nearly 1 billion putative small proteins from the global microbiome as a publicly-available resource, and highlight how some highly prevalent and evolutionarily conserved sequences lack functional annotation.

    • Yiqian Duan
    • Célio Dias Santos-Júnior
    • Luis Pedro Coelho
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-11

  • Understanding the factors underlying colonization of donor microbes in recipients of fecal microbiota transplantation is a necessary first step to aid development of directed approaches that aim to couple colonization to clinical outcomes.

    • Thomas S. B. Schmidt
    • Simone S. Li
    • Peer Bork
    ResearchOpen Access
    Nature Medicine
    Volume: 28, P: 1902-1912

  • Smoldering MM (SMM) is a premalignant stage of multiple myeloma (MM). Here the authors perform whole genome sequencing of unique paired samples of SMM progressing to MM, and show that the genomic landscape at the SMM stage is very similar to MM, but trajectories of evolution can vary from patient to patient.

    • Niccolò Bolli
    • Francesco Maura
    • Nikhil Munshi
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-10

  • Multiple myeloma evolves continuously. Here the authors chronologically reconstruct driver events in multiple myeloma, noting a limited repertoire of initiating driver events that shape the evolutionary trajectory of the disease.

    • Francesco Maura
    • Niccoló Bolli
    • Peter J. Campbell
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-12

  • Whole-genome sequencing of normal blood cells sampled from 241 adults is used to infer mosaic point mutations that are likely to have arisen during early embryogenesis, providing insight into how early cellular dynamics may affect adult tissues.

    • Young Seok Ju
    • Inigo Martincorena
    • Michael R. Stratton
    Research
    Nature
    Volume: 543, P: 714-718