In contrast to tactile sensations, proprioceptive cortical coding is barely studied in the mammalian brain. Here, using calcium imaging and optogenetic silencing experiments during a forelimb displacement paradigm in mice, the authors locate the proprioceptive cortex to both sensory and motor cortex, and further find passive limb movements to be encoded as a spatial direction vector interfacing the limb with the body’s peripersonal space.
- Ignacio Alonso
- Irina Scheer
- Mario Prsa
