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Showing 1–4 of 4 results

Advanced filters: Author: Anupama Ramachandran Clear advanced filters

Cryo-EM structures reveal coordinated domain motions that govern DNA cleavage by Cas9

Cryo-EM structures of the active Cas9–sgRNA–DNA complex in the presence of Mg²⁺ capture Cas9 in the pre- and postcatalytic states as well as in the product-bound state, and reveal coupled domain motions and interactions between the enzyme and nucleic acids.

Xing Zhu
Ryan Clarke
Sriram Subramaniam
Research08 Jul 2019
Nature Structural & Molecular Biology

Volume: 26, P: 679-685
Evaluating the insecticidal potential of alkaloids for the management of Thrips palmi: in vivo and in silico perspectives

Shyam Kumar Gupta
Abhishek Mandal
Anirban Dutta
ResearchOpen Access14 Nov 2024
Scientific Reports

Volume: 14, P: 1-18
Inactivated whole-virion vaccine BBV152/Covaxin elicits robust cellular immune memory to SARS-CoV-2 and variants of concern

Analysis of the humoral and cellular immune response to the BBV152/Covaxin inactivated vaccine reveals that it induces a robust SARS-CoV-2-specific immune memory that persists for at least 6 months and shows somewhat reduced efficiency against SARS-CoV-2 variants.

Rajesh Vikkurthi
Asgar Ansari
Nimesh Gupta
Research09 Jun 2022
Nature Microbiology

Volume: 7, P: 974-985
Neurotic personality trait as a predictor in the prognosis of composite restorations: A 24-month clinical follow up study

Sulthan Ibrahim Raja Khan
Dinesh Rao
Jagan Kumar Baskaradoss
ResearchOpen Access25 Aug 2021
Scientific Reports

Volume: 11, P: 1-13