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Showing 1–2 of 2 results
Advanced filters: Author: Arezoo Esrafili Clear advanced filters

  • Effects of biomaterials crystallinity on immune response is poorly understood. Here the authors show that the degree of crystallinity determines adjuvant-like effects of covalent organic framework (COF) biomaterial, with lower crystallinity correlating with better anti-tumour effects in multiple mouse tumour models.

    • Arezoo Esrafili
    • Abhirami Thumsi
    • Abhinav P. Acharya
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-14

  • While glycolysis inhibition impairs cancer cell tumourigenic capacities, it also affects immune cells anti-tumour activity. Here, the authors show that rescuing glycolytic inhibition of dendritic cells improves the efficacy of combining immunotherapy with glycolysis inhibition.

    • Sahil Inamdar
    • Abhirami P. Suresh
    • Abhinav P. Acharya
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-12