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Advanced filters: Author: Arlene K. Ngor Clear advanced filters

  • Artificial genetic polymers (XNAs) have been explored for their nuclease activity, but XNAzymes have proven challenging to discover by in vitro selection. Here, the authors generate an efficient RNA-cleaving 2’-fluoroarabino nucleic acid enzyme (FANAzyme) by in vitro evolution using natural DNA polymerases.

    • Yajun Wang
    • Arlene K. Ngor
    • John C. Chaput
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-10