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Showing 1–4 of 4 results
Advanced filters: Author: Armita Nourmohammad Clear advanced filters

  • Successful induction of broadly neutralizing antibodies is a main challenge in HIV vaccine development. The authors provide a framework to determine probabilities of antibody sequence development and show that uninfected and chronically infected individuals have the same chances to develop HIV-1 neutralizing antibodies.

    • Christoph Kreer
    • Cosimo Lupo
    • Florian Klein
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-14

  • Control can be applied to alter the ecological or evolutionary trajectory of a target system towards a predefined objective. In this Review, the authors discuss the aims, applications, mechanisms and dynamics of eco-evolutionary control across different biological systems.

    • Michael Lässig
    • Ville Mustonen
    • Armita Nourmohammad
    Reviews
    Nature Reviews Genetics
    Volume: 24, P: 851-867

  • Antigenic site B in influenza A virus hemagglutinin (HA) is immunodominant in circulating human H3N2 strains. Using deep mutational scanning, Wu et al. here define the local fitness landscapes of HA antigenic site B in six human H3N2 strains, providing insights into evolvability of influenza antigenicity.

    • Nicholas C. Wu
    • Jakub Otwinowski
    • Ian A. Wilson
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-10