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Showing 1–4 of 4 results
Advanced filters: Author: Artur Llobet Clear advanced filters

  • Cecilia Velasco and Artur Llobet study how autapses respond to synapse elimination. They employ microisland cultures free of glial cells, treat with a SPARC-derived peptide and show that neurons forming autaptic circuits continuously sense and regulate the number of contacts and neurotransmitter release.

    • Cecilia D. Velasco
    • Artur Llobet
    ResearchOpen Access
    Communications Biology
    Volume: 3, P: 1-13

  • Alloswitch-1 is a photoswitchable modulator for mGlu5, and it is the first photoswitchable allosteric GPCR modulator. It was generated by adding the azobenzene Ar-N=N-Ar scaffold into an existing positive allosteric modulator of the receptor.

    • Silvia Pittolo
    • Xavier Gómez-Santacana
    • Pau Gorostiza
    Research
    Nature Chemical Biology
    Volume: 10, P: 813-815

  • The formation and maturation of the neuromuscular junction require the concerted efforts of the presynaptic nerve terminal, the postsynaptic muscle fibre and perisynaptic Schwann cells. In this Review, Robitaille and colleagues describe the molecular and activity-dependent processes that underlie the development of neuron–muscle contacts.

    • Houssam Darabid
    • Anna P. Perez-Gonzalez
    • Richard Robitaille
    Reviews
    Nature Reviews Neuroscience
    Volume: 15, P: 703-718