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Advanced filters: Author: Asgar Hussain Ansari Clear advanced filters
  • Francisella novicida Cas9 (FnCas9) has low cellular editing ability which limits its therapeutic utilities. Here, the authors rationally engineer the protein to develop enhanced FnCas9 (enFnCas9) variants with high on-target editing efficiency, high precision, broadened target range, and flexible base editing outcomes.

    • Sundaram Acharya
    • Asgar Hussain Ansari
    • Debojyoti Chakraborty
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-23