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Advanced filters: Author: Ason C.-Y. Chiang Clear advanced filters

Two mitochondrial DNA polymorphisms modulate cardiolipin binding and lead to synthetic lethality

Chiang et al. map a genetic interaction in animal mitochondrial DNA by recombination. This reveals how polymorphisms in two complex IV subunits jointly affect cardiolipin binding to impact complex stability, organismal fitness and disease expression.

Ason C. Y. Chiang
Jan Ježek
Hansong Ma
ResearchOpen Access19 Jan 2024
Nature Communications

Volume: 15, P: 1-11
spict, a cyst cell-specific gene, regulates starvation-induced spermatogonial cell death in the Drosophila testis

Ason C.-Y. Chiang
Heiko Yang
Yukiko M. Yamashita
ResearchOpen Access10 Jan 2017
Scientific Reports

Volume: 7, P: 1-13

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Two mitochondrial DNA polymorphisms modulate cardiolipin binding and lead to synthetic lethality

spict, a cyst cell-specific gene, regulates starvation-induced spermatogonial cell death in the Drosophila testis

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