Nature Search

Reliable neuronal logic devices from patterned hippocampal cultures

The computational capability of the brain remains a mystery. Some insight might come from a series of experiments in which cultures of living neurons are patterned in a way to form functional logic devices.

Ofer Feinerman
Assaf Rotem
Elisha Moses
Research12 Oct 2008
Nature Physics

Volume: 4, P: 967-973
Visual interpretability of image-based classification models by generative latent space disentanglement applied to in vitro fertilization

Identifying complex patterns through deep learning often comes at the cost of interpretability. Focusing on the interpretation of classification of in vitro fertilization embryos, the authors present DISCOVER, an approach that enables visual interpretability of image-based classification models.

Oded Rotem
Tamar Schwartz
Assaf Zaritsky
ResearchOpen Access27 Aug 2024
Nature Communications

Volume: 15, P: 1-19
Gastrointestinal side effects of incretin-based obesity management medications: insights from healthcare professionals and patients’ experiences

Rotem Refaeli
Gizel Green
Shiri Sherf-Dagan
Research28 Aug 2025
International Journal of Obesity

P: 1-10
Cyclic GMP–AMP signalling protects bacteria against viral infection

cGAMP signalling in bacteria mediates anti-phage defence, as part of a genetic system suggested to be the ancient ancestor of the animal cGAS–STING innate immune pathway.

Daniel Cohen
Sarah Melamed
Rotem Sorek
Research18 Sept 2019
Nature

Volume: 574, P: 691-695
Deep phenotyping of health–disease continuum in the Human Phenotype Project

Deep phenotyping of an ancestrally diverse group of 13,000 individuals in the Human Phenotype Project highlights diversity and variations in lifestyle factors, clinical features and molecular signatures of health and disease.

Lee Reicher
Smadar Shilo
Eran Segal
Research15 Jul 2025
Nature Medicine

Volume: 31, P: 3191-3203
Single-cell ChIP-seq reveals cell subpopulations defined by chromatin state

Chromatin state is analyzed for the first time in single cells, revealing new cell subpopulations.

Assaf Rotem
Oren Ram
Bradley E Bernstein
Research12 Oct 2015
Nature Biotechnology

Volume: 33, P: 1165-1172
Bispecific antibodies increase the therapeutic window of CD40 agonists through selective dendritic cell targeting

Dahan and colleagues develop bispecific antibodies to overcome toxicities associated with CD40 agonists by preferentially targeting CD40 activation to dendritic cells, demonstrating effective antitumor immunity in multiple murine solid tumor models.

Ran Salomon
Hagar Rotem
Rony Dahan
Research21 Feb 2022
Nature Cancer

Volume: 3, P: 287-302
Clinical outcomes in estrogen receptor-positive early-stage breast cancer patients with Recurrence Score 26-30: observational real-world cohort study

Ofer Rotem
Idit Peretz
Salomon M. Stemmer
ResearchOpen Access02 Jun 2023
npj Breast Cancer

Volume: 9, P: 1-8
Atomic force microscopy characterization of kinase-mediated phosphorylation of a peptide monolayer

Roman Zhuravel
Einav Amit
Danny Porath
ResearchOpen Access14 Nov 2016
Scientific Reports

Volume: 6, P: 1-6
MAFG-driven astrocytes promote CNS inflammation

Single-cell RNA sequencing of cells from humans with multiple sclerosis and mice with a model of the disease identifies a population of disease-promoting astrocytes in which anti-oxidant and anti-inflammatory proteins are suppressed.

Michael A. Wheeler
Iain C. Clark
Francisco J. Quintana
Research12 Feb 2020
Nature

Volume: 578, P: 593-599
Visual interpretability of bioimaging deep learning models

The success of deep learning in analyzing bioimages comes at the expense of biologically meaningful interpretations. We review the state of the art of explainable artificial intelligence (XAI) in bioimaging and discuss its potential in hypothesis generation and data-driven discovery.

Oded Rotem
Assaf Zaritsky
Comments & Opinion09 Aug 2024
Nature Methods

Volume: 21, P: 1394-1397
Terrestrial and marine influence on atmospheric bacterial diversity over the north Atlantic and Pacific Oceans

Atmospheric bacterial diversity in spring indicates a strong marine influence over the Pacific and terrestrial influence over the Atlantic Ocean, according to a comparison of microbial community compositions in the north Pacific and Atlantic surface oceans and atmosphere.

Naama Lang-Yona
J. Michel Flores
Assaf Vardi
ResearchOpen Access20 May 2022
Communications Earth & Environment

Volume: 3, P: 1-10
Interplay between hippocampal TACR3 and systemic testosterone in regulating anxiety-associated synaptic plasticity

Magdalena Natalia Wojtas
Marta Diaz-González
Shira Knafo
ResearchOpen Access22 Dec 2023
Molecular Psychiatry

Volume: 29, P: 686-703
Long-term viability and function of transplanted islets macroencapsulated at high density are achieved by enhanced oxygen supply

Yoav Evron
Clark K. Colton
Avi Rotem
ResearchOpen Access25 Apr 2018
Scientific Reports

Volume: 8, P: 1-13
Hyperbaric oxygen therapy improves neurocognitive functions and symptoms of post-COVID condition: randomized controlled trial

Shani Zilberman-Itskovich
Merav Catalogna
Shai Efrati
ResearchOpen Access12 Jul 2022
Scientific Reports

Volume: 12, P: 1-10

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